BHF Oxbridge Centre of Regenerative Medicine (CRM) has allocated £371,097 to pump-priming to support innovative ideas that need to produce preliminary data before submitting a project grant application to an external funding body.
The first round of pump-priming took place in 2014 with call for applications in May, external peer review over the summer, and decisions made in August 2014. In total, five out of eight applications were approved with a total of £107,000 awarded.
The second round of pump-priming took place in 2015 with call for applications in February, and decisions made in April 2015 following an external peer review. In total, seven out of seven application were approved with a total of £168,000 awarded.
Following a budget review in 2016, a third round of pump-priming was announced in November 2016 and decisions made in Janury 2017. In total, four out of six applications were approved with a total of £96,097 awarded.
Our current award holders are listed below.
|Prof Shoumo Bhattacharya||
|Targeting RASopathic fibrosis signalling pathways using monobodies (Theme 3)||£17,900||2014|
|Prof David Greaves||
|CD68-Luciferase reporter mice for in vivo imaging of monocyte recruitment in repair (Theme 3)||£26,000||2014|
|Dr Nicola Smart||Oxford||SRSF3: a novel splicing regulator of epicardial gene networks? (Theme 1)||£12,738||2014|
|Dr Helle Jorgensen||Cambridge||In vivo proliferation of vascular smooth muscle cells (Themes 1 & 2)||£22,479||2014|
|Prof Roger Pedersen||Cambridge||Generation of human pluripotent stem cell lines capable of reporting cardiac chamber-specific differentiation (Theme 2)||£27,922||2014|
|Prof Jurgen Schneider||Oxford||Tracking stem cells in the living myocardium using 19F-MRI - a new paradigm for optimising preclinical studies (Theme 1)||£29,995||2015|
|Dr Tilly Mommersteeg||Oxford||Heart regeneration: is it in the blood? (Themes 1 & 3)||£29,960||2015|
|Dr Nicola Smart||Oxford||Sulfatases: novel targets for enhancing regeneration by epicardium-derived cells? (Theme 1)||£17,472||2015|
|Prof Shankar Srinivas||Oxford||Characterising the initiation of coordinated calcium transients in the developing heart (Theme 1)||£27,617||2015|
|Prof Paul Martin||Bristol||Development of novel software for live imaging inflammatory cell interactions in the beating heart (Themes 1 & 3)||£16,281||2015|
|Dr Helle Jorgensen||Cambridge||Developing a Crispr/Cas9-mediated system for regulation of local chromatin configuration (Theme 1)||£23,678||2015|
|Dr Amer Rana||Cambridge||Modelling cardiomyocyte biology in pulmonary arterial hypertension using induced pluripotent stem cells (Theme 2)||£23,100||2015|
|Prof Shoumo Bhattacharya||Oxford||Targeting cardiac inflammation in post-infarction myocardial injury using novel chemokine-ligand traps derived from tick saliva (Theme 3)||£20,474||2016|
|Dr Nicola Smart||Oxford||Generating new transgenic models to study the coronary vasculature (Theme 1)||£24,595||2016|
|Prof Paul Martin||Bristol||Development of novel zebrafish models to analyse endogenous extracellular vesicle trafficking during the cardiac injury response and subsequent regeneration (Themes 1 & 3)||£28,118||2016|
|Dr Helle Jorgensen||Cambridge||Investigation of vascular smooth muscle cell heterogeneity (Themes 1 & 2)||£22,910||2016|