Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

We provide two examples to illustrate the use of intersectional genetics for more precise gene targeting in vivo, namely manipulation of genes in blood vessels of the heart and brain. More broadly, this system provides a valuable strategy for tissue-specific gene manipulation that can be widely applied to other fields of biomedical research.

Original publication

DOI

10.1161/circresaha.118.312981

Type

Journal article

Journal

Circulation Research

Publisher

Lippincott Williams & Wilkins Ltd.

Publication Date

15/05/2018

Addresses

Key Laboratory of Nutrition and Metabolism, Shanghai Institutes for Biological Sciences.