Colleges
Websites
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Institute of Developmental & Regenerative Medicine
IDRM is a unique flagship institute at the University of Oxford combining insights into organ development and regeneration to treat birth defects and acquired disease
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British Heart Foundation
BHF Professor of Regenerative Medicine
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Foundation Leducq
Programming the Failing Heart to a Regenerative State
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Publications
Link to PubMed
Paul Riley
PhD, BSc
BHF Professor of Regenerative Medicine & Chair of Development and Cell Biology
Paul Riley took up the Chair of Development and Cell Biology in the Department of Physiology, Anatomy and Genetics on 1st October 2011, having been awarded a British Heart Foundation Personal Chair of Regenerative Medicine to support this position. He is also director of a recently established BHF Oxbridge Centre for Regenerative Medicine. He was previously Professor of Molecular Cardiology at the UCL-Institute of Child Health, London, where he was a principal investigator within the Molecular Medicine Unit at UCL-ICH since 1999. Prior to this, he obtained his PhD at UCL (1992-1995) and completed post-doctoral fellowships at the Samuel Lunenfeld Research Institute, Toronto, Canada and the Weatherall Institute of Molecular Medicine, Oxford (1996-1999). In 2008, Professor Riley was awarded the Outstanding Achievement Award of the European Society of Cardiology (ESC) Council on Basic Sciences. The award recognises a landmark discovery in the field of basic cardiovascular science when his team found that Thymosin b4 could mobilise dormant cells from adult epicardium to form new blood vessels in the heart, a major step towards finding a DIY mechanism to repair injury following a heart attack. Currently Professor Riley's team are focusing on exploiting the full potential of activated epicardial cells towards regenerating adult heart and understanding the mechanisms of activation of this lineage to extrapolate to human patients suffering from cardiovascular disease.
Key publications
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Journal article
Klotz L. et al, (2015), Nature, 522, 62 - 67
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Journal article
Balmer GM. et al, (2014), Nat Commun, 5
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Journal article
Risebro CA. et al, (2012), Circ Res, 111, e19 - e31
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Journal article
Smart N. et al, (2011), Nature, 474, 640 - 644
Recent publications
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Journal article
Cooper STE. et al, (2024), Arterioscler Thromb Vasc Biol
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Journal article
Weinberger M. and Riley PR., (2023), Nat Rev Cardiol
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Journal article
Chong-Morrison V. et al, (2023), Biol Open, 12
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Preprint
Lupu I-E. et al, (2022)
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Journal article
DA COSTA RODRIGUES SIMOES ANA. and RILEY P., (2022), Development (Cambridge)