Cardiovascular Stem Cell Physiology
(Identification, characterisation and recruitment)
- elucidate mechanisms regulating cardiovascular progenitor fate determination, homeostasis and recruitment after cardiac injury;
- enlist human developmental biology resource (HDBR) for characterising cardiovascular progenitors from human foetal tissue;
- compare the transcriptional networks and epigenetic status of embryonic heart progenitors during cardiogenesis with activated adult progenitors to underpin reactivation and repair.