Mi Jun Keng
BHF CRE GRADUATE STUDENT IN CARDIOVASCULAR POPULATION HEALTH SCIENCES
Project: BHF CRE GRADUATE STUDENT IN CARDOVASCULAR POPULATION HEALTH SCIENCES
Supervisors: Borislava Mihaylova, Jose Leal and Lousie Bowman
My thesis is focused on developing a framework to model lifetime outcomes for people with diabetes using data from the ASCEND study, one of the largest trial in people with diabetes. The framework can be used to assess net benefit of treatment for people with diabetes, by bringing together evidence of benefits and harms associated with the treatment, and quantifying these in terms of impact on healthcare costs and patient’s quality of life.
The ASCEND trial provides an interesting case study and the developed framework will be used to assess the cost-effectiveness of aspirin use for primary prevention of cardiovascular disease in people with diabetes, accounting for both cardiovascular benefits and bleeding risks associated with aspirin use, and possibly identify subgroup of people where aspirin use is cost-effective.
I chose this topic as it aligns with my interest in developing and applying analytical models for optimising resource use. The experience of working with large clinical trial data has also been extremely valuable. I hope to be able to further develop my skills and further my research in the area of disease modelling beyond my degree.
BSc (Hons) Mathematical Sciences, Nanyang Technological University (NTU) - 2014
MSc Management Science (Operational Research), London School of Economics and Political Science (LSE) - 2016
01/10/2018 to 30/09/2021
Hospital costs associated with adverse events in people with diabetes in the UK
Keng MJ. et al, (2022), Diabetes, Obesity and Metabolism
Decrements in health-related quality of life associated with adverse events in people with diabetes.
Keng MJ. et al, (2022), Diabetes Obes Metab, 24, 530 - 538
Impact of adverse events on hospital costs and health-related quality of life in people with diabetes
Keng MJ. et al, (2022), DIABETES RESEARCH AND CLINICAL PRACTICE, 186
Impact of adverse events on quality of life and hospital costs in secondary cardiovascular disease prevention
Lui NMJ. et al, (2021), EUROPEAN HEART JOURNAL, 42, 3159 - 3159
Performance of the UKPDS Outcomes Model 2 in a contemporary UK type 2 diabetes trial cohort
Keng MJ. et al, (2021), Value in Health