Contact information
+44 (0)1865 572846
Fax +44 (0)1865 740449
Laura Bourne
laura.bourne@cardiov.ox.ac.uk
Research groups
Colleges
Websites
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Cardiovascular Clinical Research Facility
Clinical facility
- Paul Leeson
DPhil Supervisor Profile
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Physician
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and Head of the Oxford Cardiovascular Clinical Research Facility. He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence to improve the clinical tools already available to identify those at risk, such as stress echocardiography, and identify next generation imaging and management approaches.
He sits on the NIHR Invention for Innovation funding panel and UK Biobank Imaging Advisory Board. In addition, he is a National Cardiology Lead for the NIHR Clinical Research Network and member of research collaborative working groups within the European Association of Preventive Cardiology, British Cardiovascular Society and British and Irish Hypertension Society.
Key publications
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Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
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Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults
Journal article
Huckstep OJ. et al, (2018), Journal of the American College of Cardiology
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Journal article
Dey D. et al, (2019), J Am Coll Cardiol, 73, 1317 - 1335
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Journal article
Corral-Acero J. et al, (2020), European Heart Journal
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Journal article
Lewandowski AJ. et al, (2013), Circulation, 128, 713 - 720
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Journal article
Siepmann T. et al, (2017), Neurology, 88, 1256 - 1264
Recent publications
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The effects of an aerobic training intervention on cognition, grey matter volumes and white matter microstructure.
Journal article
Sexton CE. et al, (2020), Physiol Behav, 223
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Changes in the preterm heart from birth to young adulthood: a meta-analysis
Journal article
Telles F. et al, (2020), Pediatrics, 146
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The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions.
Journal article
Littlejohns TJ. et al, (2020), Nat Commun, 11
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Multimodality Imaging Demonstrates Reduced Right-Ventricular Function Independent of Pulmonary Physiology in Moderately Preterm-Born Adults.
Journal article
Mohamed A. et al, (2020), JACC Cardiovasc Imaging
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Variations in Cardiovascular Structure, Function, and Geometry in Midlife Associated With a History of Hypertensive Pregnancy.
Journal article
Boardman H. et al, (2020), Hypertension (Dallas, Tex. : 1979), HYPERTENSIONAHA11914530 - HYPERTENSIONAHA11914530