Rebecca M A Sitsapesan
Emeritus Professor of Pharmacology
I hold a BSc in Pharmacology (Aberdeen), an MSc in Cardiovascular Studies (Leeds) and a PhD in Cardiac Physiology and Pharmacology (Strathclyde). My post-doctoral research into ion-channel biophysics began at the University of Glasgow and continued at the National Heart & Lung Institute at Imperial College, London.
In 1991, I was awarded a British Heart Foundation Basic Science Lectureship to investigate the function of cardiac intracellular Ca2+-release channels and a University Lectureship at Imperial College. I moved to Bristol in 2001 and was promoted to Professor of Pharmacology in 2011. In August 2013, I became Professor of Pharmacology at the University of Oxford.
In June 2019, I retired from the Department of Pharmacology and now hold the position of Emeritus Professor.
Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength
Elbaz M. et al, (2019), Human Molecular Genetics
Enhanced activity of multiple TRIC-B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents.
O'Brien F. et al, (2019), J Physiol, 597, 2691 - 2705
Cooperative Gating Among Ion-Channel Species in Junctional Sarcoplasmic Reticulum
Venturi E. et al, (2019), BIOPHYSICAL JOURNAL, 116, 521A - 521A
Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour
LINDSAY CJ. et al, (2018), Scientific Reports
Atorvastatin Activates Skeletal RyR1 Channels: Towards Reducing Statin Side-Effects
Lindsay CJ. et al, (2018), Biophysical Journal