Specific modulation of CRISPR transcriptional activators through RNA-sensing guide RNAs in mammalian cells and zebrafish embryos.

Pelea O., Mayes S., Ferry QRV., Fulga TA., Sauka-Spengler T.

DOI

10.7554/eLife.87722

Type

Preprint

Publication Date

2025-07-29T00:00:00+00:00

Keywords

CRISPR, RNA biomarkers, conditional activation, genetics, genomics, synthetic biology, zebrafish, Zebrafish, Animals, RNA, Guide, CRISPR-Cas Systems, HEK293 Cells, Humans, CRISPR-Cas Systems, Embryo, Nonmammalian, Clustered Regularly Interspaced Short Palindromic Repeats, RNA, Streptococcus pyogenes, Gene Editing, Transcriptional Activation

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