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In the late 1960s Miles Vaughan Williams, a member of the staff in the Oxford Department of Pharmacology and Fellow of Hertford College (1955-85), introduced a novel classification of drugs used to treat cardiac arrhythmias. This scheme has been very widely used around the world and has led to the development of new drugs that have saved countless lives. Our understanding of the control of cardiac rhythm has developed in that time and a group of cardiovascular scientists from Oxford, Cambridge and Beijing led by Associate Professor Ming Lei decided that the time was ripe to modernise the classification and to celebrate the centenary of the birth of Vaughan Williams.
Heather Group publishes new paper in Diabetes journal
Research
13 March 2024
Professor Lisa Heather and colleagues have just published a new paper, ‘Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of its Pathology’ in the journal Diabetes.
Professor Shankar Srinivas awarded a Wellcome Discovery Award
CRE Research
9 October 2023
Professor Shankar Srinivas (based in the IDRM), has received a Wellcome Discovery Award.
RDM research featured in Hidden Heart programme for World Heart Day
CRE Public Engagement Research
4 October 2023
Programmes lead by Oxford BHF CRE Director Professor Hugh Watkins, and Oxford BHF CRE PI Professor Charalambos Antoniades, have been featured in a special programme to mark World Heart Day.
BBSRC-funded Oxford-Cambridge consortium to close the gap in our understanding of human heart development
CRM Research
3 October 2023
A research consortium of DPAG/IDRM and University of Cambridge scientists have been awarded a major strategic grant by the Biotechnology and Biological Sciences Research Council (BBSRC) to answer the pressing long-standing questions of how the human heart grows, how it is put together, and how the different heart cells communicate with each other during pregnancy.
Synthetic peptides mimic anti-inflammatory properties of tick saliva chemicals
CRM Research
19 September 2023
Short peptides derived from anti-inflammatory ‘evasins’ released by ticks could be used to develop new treatments for anti-inflammatory disease.
Duncan Sparrow elected Supernumerary Fellow of Exeter College
CRE Research
31 July 2023
Congratulations to Associate Professor Duncan Sparrow on his appointment as Supernumerary Fellow of Exeter College, University of Oxford.
Study develops radiotranscriptomic AI analysis to enable virtual heart biopsies
CRE Research
5 September 2022
RDM researchers tested the method in COVID-19 patients, to find that the results predicted in-hospital mortality.
Joaquim Vieira brings heart regeneration research to the public at Pint of Science
Public Engagement Research
10 May 2022
Pint of Science is the world’s largest public science festival bringing researchers to local pubs, cafes and spaces to share their scientific discoveries with the public.
DPAG researchers showcased at premier European Society of Cardiology meeting
Research
5 May 2022
DPAG scientists across four research groups were highlighted at the major annual European Society of Cardiology basic science conference (FCVB 2022). Congratulations are in order for Dr KC Park on receiving the Young Investigator Award and to Dr Elisabetta Gamen on winning the Moderated Poster Prize.
RDM researchers awarded £2million MRC grant
Research
16 March 2022
Researchers at the Cardiovascular Clinical Research Facility (CCRF) have won a five year MRC funding programme to help understand how high blood pressure (hypertension) during pregnancy affects the heart, brain and blood vessels throughout the life of women, as well as the children born after such a pregnancy.
Study indicates reasons for decline in death rates from heart attacks
CRE Research
7 March 2022
A new study involving Oxford Population Health researchers finds that both prevention and improved treatments have helped reduce deaths from heart attacks - but the relative importance of each varies by country, age and sex.
Commercial development of therapeutic anti-inflammatory peptide begins
CRE Research
15 February 2022
An Oxford BHF CRE “Pump Priming” award to Professor Shoumo Bhattacharya and his research group led to a great return on investment with this exclusive licensing agreement for their innovative research.
Dr Qiang Zhang wins Society for Cardiovascular Magnetic Resonance Early Career Award 2022
CRE Research
8 February 2022
Many congratulations to Dr Qiang Zhang, Oxford BHF CRE Transition Fellow, who has won a prestigious award for his work in developing a groundbreaking technology for detecting scar in the myocardium
RDM researchers test potential treatment for fatigue in long COVID patients
Research
29 October 2021
The Radcliffe Department of Medicine’s Dr Betty Raman is leading a new a phase 2a clinical trial to investigate whether a drug could treat the fatigue and muscle weakness experienced by many patients who have recovered from COVID.
Drug could help diabetic hearts recover after a heart attack
CRE Research
20 October 2021
New research led by Associate Professor Lisa Heather has found that a drug known as molidustat, currently in clinical trials for another condition, could reduce risk of heart failure after heart attacks.
Richard Tyser and Jack Miller honoured by the British Society of Cardiovascular Research
CRE CRM Research
14 September 2021
Dr Richard Tyser is this year’s winner of the Bernard and Joan Marshall Early Career Investigator Prize, and Dr Jack Miller has received a runner-up award, at the British Society of Cardiovascular Research Autumn Meeting.
Reducing fat in the diabetic heart could improve recovery from heart attack
CRE Research
29 July 2021
New research from the Heather Group has shown that in type 2 diabetes an overload of lipids reduces the heart’s ability to generate energy during a heart attack, decreasing chances of recovery.
A mechano-receptor that induces cellular plasticity and cardiovascular disease
CRE Research
20 July 2021
High blood sugar levels ‘reprogramme’ stem cells
Research
14 July 2021
Findings explain higher risk of heart attack in people with diabetes, even after treatment .
Critical six-week window to ‘reset’ blood pressure after giving birth
CRE Research
28 June 2021
Home blood pressure monitors could help mothers significantly lower high blood pressure after pregnancy