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This report describes 12 Dutch families of which at least two members have had Guillain-Barre syndrome (GBS). The authors observed an earlier onset of GBS in successive generations. The occurrence of GBS within families suggests a role for genetic factors in the pathogenesis of GBS.

Original publication

DOI

10.1212/01.wnl.0000143055.09646.31

Type

Journal article

Journal

Neurology

Publication Date

09/11/2004

Volume

63

Pages

1747 - 1750

Keywords

Adult, Age of Onset, Aged, Child, Child, Preschool, Female, Genetic Predisposition to Disease, Guillain-Barre Syndrome, Humans, Infant, Newborn, Male, Middle Aged, Pedigree