Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia.

Jatho A., Zieseniss A., Brechtel-Curth K., Yamamoto A., Coleman ML., Vergel Leon AM., Biggs D., Davies B., Pugh CW., Ratcliffe PJ., Katschinski DM.

DOI

10.1161/CIRCRESAHA.120.318216

Type

Journal article

Publication Date

2021-04-16T00:00:00+00:00

Volume

128

Pages

1208 - 1210

Total pages

2

Keywords

doxycycline, heart failure, incidence, myocardial infarction, prolyl hydroxylase, Animals, Hypoxia-Inducible Factor 1, alpha Subunit, Mice, Myocardial Infarction, Procollagen-Proline Dioxygenase, RNA Interference, RNAi Therapeutics

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