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We report a rare complication following transfusion of a large volume of blood in an adult patient. An electrophysiological disturbance of the cardiac cycle with prolongation of the QT interval developed, which was followed by recurrent episodes of torsade de pointes, a unique form of ventricular tachycardia. The most likely cause of this acquired long QT syndrome was hypomagnesaemia secondary to massive blood transfusion. Treatment with a magnesium infusion restored the QT interval to normal and temporary ventricular pacing prevented further ventricular arrhythmias.


Journal article

Publication Date





125 - 127


Adult Blood Transfusion/*adverse effects Case Report Electrocardiography Female Human Long QT Syndrome/*etiology Magnesium/blood/therapeutic use Magnesium Deficiency/*complications/etiology Torsades de Pointes/*etiology