Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Schlemminger I., Mole DR., McNeill LA., Dhanda A., Hewitson KS., Tian Y-M., Ratcliffe PJ., Pugh CW., Schofield CJ.
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.