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After more than a decade of hope and hype, researchers are finally making inroads into understanding the genetic basis of many common human diseases. The use of genome-wide association studies has broken the logjam, enabling genetic variants at specific loci to be associated with particular diseases. Genetic association data are now providing new routes to understanding the aetiology of disease, as well as new footholds on the long and difficult path to better treatment and disease prevention.

Original publication

DOI

10.1038/nature07631

Type

Journal article

Journal

Nature

Publication Date

11/12/2008

Volume

456

Pages

728 - 731

Keywords

Genetic Predisposition to Disease, Genetic Privacy, Genome-Wide Association Study, Genotype, Humans, Phenotype, Risk