Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.

Original publication

DOI

10.1016/j.devcel.2017.01.008

Type

Journal article

Journal

Developmental cell

Publication Date

02/2017

Volume

40

Pages

215 - 216

Addresses

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK. Electronic address: shankar.srinivas@dpag.ox.ac.uk.

Keywords

Blastocyst, Animals, Mice, Cell Differentiation, Embryo, Mammalian