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Creutzfeldt-Jakob disease (CJD) can be transmitted through human growth hormone or gonadotrophin administration, dura mater or cornea transplantation, depth EEG monitoring and the use of contaminated neurosurgical instruments. We describe the first two dura mater associated CJD cases in the Netherlands. Ten and fourteen years before the onset of symptoms both patients received a Lyodura implantation. Findings are discussed in light of the growing epidemic of CJD among dura mater recipients.


Journal article


J Neurol

Publication Date





877 - 880


Adult, Brain, Creutzfeldt-Jakob Syndrome, Dura Mater, Humans, Male, Middle Aged, Netherlands, Transplantation, Autologous, Transplantation, Homologous