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Search results (182)

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Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres.

Kerckhoffs A. et al, (2026), Nat Chem

Mechanism of GPR84 allosteric modulation at a helix 8-proximate site.

Zhang X. et al, (2026)

Near-Infrared Triggered Anion Transport Induces Cancer Cell Death.

Ahmad M. et al, (2026), Angew Chem Int Ed Engl, 65

Fluorescently labelled polypropylene as a model microplastic for cellular imaging

Evans A. et al, (2026), Polymer Chemistry

Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis.

Sereesongsaeng N. et al, (2025), Elife, 14

A Data-Driven Perspective on Bioisostere Evaluation: Mapping the Benzene Bioisostere Landscape with BioSTAR.

Hernández-Lladó P. et al, (2025), J Med Chem, 68, 16921 - 16939

Steric control of signaling bias in the immunometabolic receptor GPR84.

Wang P. et al, (2025), bioRxiv

It should be free to apply to graduate school.

Fernando B. et al, (2025), Nature, 643

Spontaneously Immortalised Nonhuman Primate Müller Glia Cell Lines as Source to Explore Retinal Reprogramming Mechanisms for Cell Therapies.

Salman A. et al, (2025), J Cell Physiol, 240

Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

Sereesongsaeng N. et al, (2024)

Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration.

Choudhury C. et al, (2024), ACS Pharmacol Transl Sci, 7, 2326 - 2332

Synthesis of Aryl-fused Bicyclo[3.1.1]heptanes (BCHeps) and Validation as Naphthyl Bioisosteres

Kerckhoffs A. et al, (2024)

Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia.

Cogswell TJ. et al, (2024), RSC Med Chem, 15, 3495 - 3506

Biased agonists of GPR84 and insights into biological control.

Luscombe VB. et al, (2024), Br J Pharmacol, 181, 1509 - 1523

Correction: Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2).

Kennett A. et al, (2024), Chem Commun (Camb), 60

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