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A collaborative paper from the De Val and Smart Groups has established multiple regulatory pathways responsible for the formation of blood vessels in the developing heart. In doing so they have identified a crucial pathway that is repressed in the adult heart after injury, which may hold the key to a new and improved strategy for repair.
Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance
Journal article
Pavlova S. et al, (2026), Extracellular Vesicle, 7
Plasma extracellular vesicle modulate immune cell transcriptional responses following acute myocardial infarction
Journal article
Timms L. et al, (2026), Iscience, 29
A functional overlap between actively transcribed genes and chromatin insulator elements.
Journal article
Cornell LJ. et al, (2026), EMBO J
YdbL directly modulates YdbH-YnbE bridge formation to maintain Escherichia coli outer membrane homeostasis
Preprint
De'Ath C. et al, (2026)
Dopamine release from Parkinson's patient-derived neurons is disrupted due to impaired synaptic vesicle loading
Preprint
Cramb KML. et al, (2026)
Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement.
Journal article
Tse KYK. et al, (2026), Sleep
Senescence-related myocardial dysfunction: keeping a young heart.
Journal article
Ajjan RA. et al, (2026), Eur Heart J
Reimagining Thomas Lewis's perspective: using artificial intelligence tools to predict cardiovascular risk from computed tomography.
Journal article
Kotronias RA. et al, (2026), Heart
Associations of 6600 SomaScan proteins with demographic, lifestyle, environmental and health characteristics in Chinese adults
Journal article
CHEN Z. et al, (2026), Scientific Reports
Young adulthood adiposity in relation to all-cause and cause-specific mortality: a prospective study of 0.5 million Chinese adults
Journal article
CHEN Z. et al, (2026), Science Bulletin
Single intramuscular injection of self-amplifying RNA of Nppa to treat myocardial infarction.
Journal article
Zhang K. et al, (2026), Science, 391
The metabolic balancing act between fatty acid and glucose substrate use for optimal myocardial function: Key role for membrane substrate transporters.
Journal article
Glatz JFC. et al, (2026), Am J Physiol Heart Circ Physiol
Causes of excess non-lymphoma death in 58,000 patients with DLBCL diagnosed during 1997-2020 and followed for up to 25 years.
Journal article
Challenger A. et al, (2026), Blood Adv
Diagnostic accuracy, treatment and prognosis of myocardial infarction: an 11-year follow-up of a community-based cohort of 0.5 million Chinese adults
Journal article
CHEN Z. et al, (2026), BMJ Public Health
Harnessing Phase Separation for the Development of High-Performance Hydrogels.
Journal article
Shao Y. et al, (2026), Adv Sci (Weinh)
Changes in absolute coronary blood flow and myocardial resistance after percutaneous coronary intervention.
Journal article
Marin F. et al, (2026), EuroIntervention, 22, e301 - e312
An interpretable and explainable neural network to classify sports-related cardiac arrhythmias in professional football athletes
Preprint
Vanegas Mueller E. et al, (2026)
Urinary carbonic anhydrase 1 excretion is a marker of hemolysis-triggering conditions suitable for point-of-care testing.
Journal article
Hulikova A. et al, (2026), Blood Glob Hematol, 2
Relief with a catch: hemodilution in chronic mountain sickness sparks an erythropoietin surge.
Journal article
Villafuerte FC. and Swietach P., (2026), Blood Red Cells Iron, 2