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A new paper from the Heather and Tyler groups has uncovered the mechanism responsible for reduced energy in the hearts of patients with type 2 diabetes and revealed a new therapeutic strategy to reverse the energy deficit.
Overcoming the challenges of genome-editing essential genes
Journal article
Teboul L. and Davies B., (2026), STAR Protocols, 7
A high-flux source of cold strontium with a loading rate of 4×1010 atoms/s for open release
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Walker T. et al, (2026), Avs Quantum Science, 8
Cardiac energetics in health and disease: a meta-analysis.
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Bray JJH. et al, (2026), Eur Heart J Imaging Methods Pract, 4
Multi-organ structural and functional deficits in association with long COVID: a population-based case-control study
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Fernández-Sanlés A. et al, (2026), Eclinicalmedicine, 98
Proteomic organ-specific signatures, ageing traits, disease risks and genetic architecture in an East Asian population.
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Bennett DA. et al, (2026), EBioMedicine, 130
The need for a balanced perspective on tobacco cessation and taxation
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LEWINGTON S. et al, (2026), Addiction
Predictors and Prognostic Significance of Cardiac Damage Progression in Non-Severe Aortic Stenosis.
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Bussmann BM. et al, (2026), Eur Heart J Cardiovasc Imaging
Comprehensive biophysical and structural profiling of alpha-actinin-2 variants reveals mechanistic diversity in hypertrophic cardiomyopathy.
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Noureddine M. et al, (2026), Nat Commun, 17
Endosomal TPC1-mediated Ca2+ nanodomains regulate transferrin receptor trafficking and iron homeostasis.
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Burton WJ. et al, (2026), Proc Natl Acad Sci U S A, 123
Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease.
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Mazidi M. et al, (2026), J Am Coll Cardiol
Multistage microrobots with pH-responsive release of platelet membrane-coated nanoparticles.
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Sun R. et al, (2026), Sci Adv, 12
Varicose projection astrocytes: Conserved reactive cells in brain pathology.
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Ciani C. et al, (2026), Sci Adv, 12
Trientine for hypertrophic cardiomyopathy: a phase 2 trial.
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Farrant JP. et al, (2026), Eur Heart J
A core transcriptional signature of human trained immunity.
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Boden KA. et al, (2026), Cell Rep, 45
ProLM: a plasma proteomics pretrained model for the general population.
Journal article
Qiu S. et al, (2026), Nat Commun
Impact of middle meningeal artery embolization timing on chronic subdural hematoma resolution and functional outcomes.
Journal article
DeMessie B. et al, (2026), J Neuroradiol, 53
MAD-MT Score: A Tool to Optimize Patient Selection for Mechanical Thrombectomy in Distal Vessel Occlusions.
Journal article
Chen H. et al, (2026), Stroke
Long-term exposure to air pollution, proteomic aging clocks, and liver-related outcomes in Chinese adults.
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Huang Y. et al, (2026), Environ Res
Myocardial Scar Assessment Using Artificial Intelligence-Powered Contrast-Free MRI: A Prospective Multicenter Study of Virtual Native Enhancement.
Journal article
Zhang Q. et al, (2026), J Am Coll Cardiol
A scalable high-throughput serolomics platform for profiling serum antibody responses in large-scale population-based cohorts.
Journal article
Kröller L. et al, (2026), Nat Protoc