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New collaborative research from the Mommersteeg Group and MRC WIMM researchers shows that a protein called Runx1 plays a significant role in the formation of the cardiac scar that forms after the heart is injured, a scar that is known to inhibit heart regeneration. In the zebrafish, a freshwater fish known to be able to fully regenerate its heart after damage, they show that the absence of Runx1 results in enhanced regeneration. This indicates a potential new therapeutic target for heart repair.
Pump-Priming Awards
The overall goal of Pump Priming awards is to allow researchers to be more responsive and innovative, and to help maximise leverage from the BHF funding. The following awards have been made to Principal Investigators of the Oxford BHF CRE and to post-doctoral researchers and collaborators across the Oxford cardiovascular research groups.