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DPAG's Dr Jakub Tomek and Professor Blanca Rodriguez's Computational Cardiovascular Science Team have developed a new computer model that recreates the electrical activity of the ventricles in a human heart. In doing so, they have uncovered and resolved theoretical inconsistencies that have been present in almost all models of the heart from the last 25 years and created a new human heart model that could enable more basic, translational and clinical research into a range of heart diseases and potentially accelerate the development of new therapies.
Manhattan++
GWAS, Manhattan plot, meta-analysis, R, software
IDRM Microscopy Oxford-ZEISS Centre of Excellence in Biomedical Imaging
Fluorescent microscopy, slide scanner, high resolution, confocal, light sheet
Flow Cytometry Facility at CHG
Multi-channel FACS, Immune phenotyping, Cardiac cell Sorting, Flowjo analysis, FACS panel design
Biobank Accelerometer Analysis Tool
Physical activity, sleep, step counts, fitness trackers, machine learning
CalTrack
Calcium signalling Calcium quantification Live/fluorescent microscopy MatLab
QuantStudio™ 7 Flex Real-Time PCR System
Genotyping & Genomic Profiling, Real Time PCR, Real Time PCR-Based Gene Expression Profiling
Organ bath
Organ bath Vasomotor Powerlab
UK Biobank (UKB) Research Analysis Platform (RAP)
UK Biobank Research Analysis Platform Multi-omics Cloud computing Big Data