Research groups
Colleges
Adam Lewandowski
BSc(Hons), MSt, DPhil, FESC
Associate Professor of Cardiovascular Science
- BHF Intermediate Research Fellow
- Deputy Director of the Oxford Cardiovascular Clinical Research Facility
Cardiovascular development and systems physiology
Adam moved from Canada to the UK in 2009 when he was awarded a Commonwealth Scholarship to fund his PhD in Cardiovascular Medicine at the University of Oxford. He completed his doctoral research in 2013 on the long-term cardiovascular impact of being born preterm and went on to complete his postdoctoral research in Oxford. As part of this, he helped refine the ultrasound imaging protocols for the UK Biobank study and developed studies to build on the findings from his doctoral research. These studies have provided more detailed characterisation of pathways leading to long-term heart changes in preterm-born individuals. The Lewandowski group has found that people born preterm that have differences in cardiac structure and function in adult life have an abnormal cardiac response to physiological stress, suggestive of a reduced myocardial functional reserve. Current studies are ongoing to better define myocardial tissue changes in the preterm heart in childhood and adulthood.
Adam's primary study funding is from a 5-year British Heart Foundation (BHF) Intermediate Basic Science Research Fellowship received in 2018. He is also a Research Fellow and College Lecturer in Systems Physiology at St Peter's College, University of Oxford where he leads on the tutorial teaching for undergraduate and graduate-entry medicine for cardiovascular physiology. Adam also recently completed a part-time master's degree in Healthcare Data Informatics at the University of Cambridge.
Key publications
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Association of Preterm Birth with Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood
Journal article
LEWANDOWSKI A. et al, (2021), Journal of the American College of Cardiology
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Journal article
Mohamed A. et al, (2021), JAMA Cardiol, 6, 821 - 829
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Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults
Journal article
Huckstep OJ. et al, (2018), Journal of the American College of Cardiology
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Breast Milk Consumption in Preterm Neonates and Cardiac Shape in Adulthood.
Journal article
Lewandowski AJ. et al, (2016), Pediatrics, 138
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Journal article
Lewandowski AJ. et al, (2013), Circulation, 128, 713 - 720
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Journal article
Lewandowski AJ. et al, (2013), Circulation, 127, 197 - 206
Recent publications
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Multiorgan Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review
Journal article
LEWANDOWSKI A. et al, (2024), Journal of the American Heart Association
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Preterm birth and cardiometabolic health trajectories from birth to adulthood: the Avon Longitudinal Study of Parents and Children
Journal article
LEWANDOWSKI A., (2024), Journal of the American Heart Association
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A Novel Role of 5-Methyl-(6S)-tetrahydrofolate in Mediating Endothelial Cell Tetrahydrobiopterin in Pregnancy and Implications for Gestational Hypertension
Journal article
Dickinson Y. et al, (2024), Hypertension