Research Projects Available
DPhil
- 2026 Raman Group: Pioneering Precision Medicine in Hypertrophic Cardiomyopathy: Advanced Imaging, Machine Learning, and Translational Research for Early Detection and Targeted Therapies — Radcliffe Department of Medicine
- 2026 Raman Group (MRC Enterprise iCase): Development of Cardiac Diffusion Tensor Imaging for Clinical Evaluation of Cardiomyopathies — Radcliffe Department of Medicine
MSc by Research
- Raman Group: Intergrating Multimodal Imaging, Genomics, and Clinical Data for Risk Stratification and Precision Therapy in Cardiomyopathies through Novel Artificial Intelligence Approaches — Radcliffe Department of Medicine
- Raman Group: Multi-Organ MRI Phenotyping for Risk Prediction in Heart Failure and Multisystem Diseases: Insights from Prospective Imaging Cohorts and UK Biobank — Radcliffe Department of Medicine
- Raman Group: AI-Enhanced ECG and Digital Twin Modelling for Early Diagnosis and Mechanistic Stratification in Cardiomyopathies — Radcliffe Department of Medicine
- Raman Group: Unravelling Mechanisms of Phenotypic Diversity in Hypertrophic Cardiomyopathy through Advanced Cardiac MRI and Patient-Specific Multi-Omic Modelling — Radcliffe Department of Medicine
- Raman Group: Enhancing Traditional and Photon-Counting CT for the Early Diagnosis and Phenotyping of Cardiomyopathies — Radcliffe Department of Medicine
Colleges
Websites
-
Sky news
Findings from the C-MORE - multiorgan MRI Study
-
BBC news
Findings from the C-MORE - multiorgan MRI Study
-
BBC world radio
Betty Raman presenting findings from the C-MORE study (8:20)
Betty Raman
MBBS DPhil FESC FRACP
Associate Professor of Cardiovascular Medicine
- NIHR South Central RRDN Cardiology Specialty Lead
- Hon. Consultant Cardiologist (Loc)
- Wellcome Career Development Award Fellow
- RDM Cardiovascular Medicine EDI Champion
Prof Betty Raman is a senior honorary consultant cardiologist specialising in advanced cardiovascular imaging (CMR and cardiac CT) and inherited and cardiomyopathic heart disease. She leads a translational research programme that bridges mechanistic discovery, clinical application, and innovation in drug development.
After completing her specialist cardiology training in Australia (FRACP), she joined the University of Oxford in 2015 to pursue a DPhil in hypertrophic cardiomyopathy, the leading cause of sudden cardiac death in young adults and athletes. Her doctoral work led to the development of a novel oxygen sensitive magnetic resonance method that detects myocardial hypoxia non-invasively and holds promise as an early biomarker of disease activity. This pioneering work has been recognised internationally through awards from the ESC, AHA, BSCMR, SCMR, and BCS.
Building on this foundation, she was awarded a British Heart Foundation Transition Fellowship (2020) and subsequently a Wellcome Career Development Award (2024) to advance a multidisciplinary research programme integrating imaging, genetics, energetics, and computational modelling. Her goal is to identify and validate early markers of disease progression in hypertrophic and related cardiomyopathies, enabling more precise risk prediction and supporting evaluation of emerging therapies.
During the COVID 19 pandemic, she led the C-MORE study, a large multicentre initiative that combined MRI, cardiopulmonary exercise testing, and cognitive assessments to characterise the long term multi organ consequences of COVID 19. This work helped shape understanding of post-viral cardiovascular and systemic recovery.
Her current research focuses on:
Early stage disease detection and monitoring in cardiomyopathies using next generation CMR including BOLD, DTI, spectroscopy, and radiomics.
Mechanistic biomarkers to support early phase and adaptive clinical trials.
Cross organ interactions in cardiometabolic disease, integrating heart, brain, liver, and renal imaging.
As a senior academic leader, she collaborates widely across academia, the NHS, and industry to translate advanced imaging into clinical and commercial impact. She actively welcomes scientific collaborators, students, and industrial partners interested in biomarker discovery, imaging enabled trial design, and AI based modelling for cardiovascular disease.
Recent publications
-
Subclinical Postpartum Renal Structure After Hypertensive Pregnancy Disorders.
Journal article
Cutler HR. et al, (2025), Hypertension
-
Sex Differences in the Genetic Causes of Dilated Cardiomyopathy
Journal article
Mangino M. et al, (2025), Journal of the American College of Cardiology, 86, 400 - 403
-
Computational modelling of myocardial metabolism in patients with advanced heart failure.
Journal article
Beyhoff N. et al, (2025), Eur J Heart Fail
-
Multiorgan Imaging for Interorgan Crosstalk in Cardiometabolic Diseases
Journal article
Devesa A. et al, (2025), Circulation Research, 136, 1454 - 1475
-
Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion
Conference paper
Yang G. et al, (2025), Proceedings - International Symposium on Biomedical Imaging
-
Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort study.
Journal article
Gharibzadeh S. et al, (2025), EClinicalMedicine, 79
-
Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations.
Journal article
Rua C. et al, (2024), Brain, 147, 4121 - 4130
-
1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID
Journal article
Finnigan LEM. et al, (2024), Radiology, 313
-
1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID.
Journal article
Finnigan LEM. et al, (2024), Radiology, 313
-
Incidence of diabetes mellitus following hospitalisation for COVID-19 in the United Kingdom: A prospective observational study.
Journal article
Tyrer F. et al, (2024), Diabetes Obes Metab
-
Diagnostic utility of electrocardiogram for screening of cardiac injury on cardiac magnetic resonance in post-hospitalised COVID-19 patients: a prospective multicenter study.
Journal article
Samat AHA. et al, (2024), Int J Cardiol, 415
-
1-year health outcomes associated with systemic corticosteroids for COVID-19: a longitudinal cohort study.
Journal article
Leavy OC. et al, (2024), ERJ Open Res, 10
-
Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension.
Journal article
Mahmod M. et al, (2024), Circ Cardiovasc Imaging, 17
-
CTEPH is an uncommon complication of COVID-19: UK national surveillance and observational screening cohort studies.
Journal article
Reddy SA. et al, (2024), Eur Respir J
-
Hypertrophic cardiomyopathy detection with artificial intelligence electrocardiography in international cohorts: an external validation study.
Journal article
Siontis KC. et al, (2024), Eur Heart J Digit Health, 5, 416 - 426
-
Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study.
Journal article
Coleman JA. et al, (2024), Cardiovascular research, cvae086 - cvae086
-
Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy.
Journal article
Coleman JA. et al, (2024), Frontiers in pharmacology, 15, 1379236 - 1379236
-
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Journal article
Liew F. et al, (2024), Nat Immunol, 25, 607 - 621
-
Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19.
Journal article
Devine K. et al, (2024), Clin Endocrinol (Oxf), 100, 317 - 327
-
NHS Health Check attendance is associated with reduced multiorgan disease risk: a matched cohort study in the UK Biobank.
Journal article
McCracken C. et al, (2024), BMC Med, 22
-
Long term effects of COVID-19 on the oral and lower airway microbiota
Conference paper
Headley DADL. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64
-
Physical performance 5 and 12 months after hospital-discharge in CCVID-19 survivors
Conference paper
Baldwin MM. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64
-
Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury.
Journal article
Taquet M. et al, (2024), Brain Commun, 6
-
Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review.
Journal article
Singh SJ. et al, (2023), Eur Respir Rev, 32
-
Electrophysiological mechanisms underlying T wave pseudonormalisation on stress ECGs in hypertrophic cardiomyopathy
Journal article
Coleman J. et al, (2023), Computers in Biology and Medicine
-
Synbiotics in post-acute COVID-19 syndrome-a potential new treatment framework?
Journal article
Raman B. and Ramasamy MN., (2023), Lancet Infect Dis
-
Long COVID research: an update from the PHOSP-COVID Scientific Summit.
Journal article
Brightling CE. et al, (2023), Lancet Respir Med, 11, e93 - e94
-
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
Journal article
C-MORE/PHOSP-COVID Collaborative Group None., (2023), Lancet Respir Med, 11, 1003 - 1019
-
Personalizing Apical Hypertrophic Cardiomyopathy Diagnosis: A Major Step Forward, but Challenges Remain.
Journal article
Raman B., (2023), JACC Cardiovasc Imaging
-
Erratum for: Lung Abnormalities Detected with Hyperpolarized 129Xe MRI in Patients with Long COVID.
Journal article
Grist JT. et al, (2023), Radiology, 309
-
Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization.
Journal article
Taquet M. et al, (2023), Nat Med
-
Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy.
Journal article
Farrant J. et al, (2023), Heart, 109, 1175 - 1182
-
Mechanisms and prognostic impact of myocardial ischaemia in hypertrophic cardiomyopathy.
Journal article
Coleman JA. et al, (2023), International Journal of Cardiovascular Imaging, 1 - 18
-
Liver disease is a significant risk factor for cardiovascular outcomes - A UK Biobank study.
Journal article
Roca-Fernandez A. et al, (2023), J Hepatol
-
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls.
Journal article
Zheng B. et al, (2023), Lancet Reg Health Eur, 29
-
Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.
Journal article
Hundertmark MJ. et al, (2023), Circulation, 147, 1654 - 1669
-
Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID)
Preprint
Elneima O. et al, (2023)
-
Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study.
Journal article
Finnigan LEM. et al, (2023), EClinicalMedicine, 59
-
Novel insights into diminished cardiac reserve in non-obstructive hypertrophic cardiomyopathy from four-dimensional flow cardiac magnetic resonance component analysis.
Journal article
Ashkir Z. et al, (2023), Eur Heart J Cardiovasc Imaging
-
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study.
Journal article
Jackson C. et al, (2023), Lancet Respir Med
-
3-Dimensional Strain Analysis of Hypertrophic Cardiomyopathy: Insights From the NHLBI International HCM Registry.
Journal article
Heydari B. et al, (2023), JACC Cardiovasc Imaging, 16, 478 - 491
-
ABNORMAL SKELETAL METABOLISM BUT NOT CARDIAC DYSFUNCTION AS A CAUSE FOR FATIGUE POST COVID-19
Conference paper
Cassar MP. et al, (2023), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 81, 1397 - 1397
-
Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization
Journal article
Taquet M. et al, (2023), NATURE MEDICINE
-
Acute changes in myocardial tissue characteristics during hospitalization in patients with COVID-19.
Journal article
Shanmuganathan M. et al, (2023), Front Cardiovasc Med, 10
-
Characteristics and risk factors for post-COVID-19 breathlessness after hospitalisation for COVID-19.
Journal article
Daines L. et al, (2023), ERJ Open Res, 9
-
Editorial: Post-COVID-19 cardiovascular sequelae.
Journal article
Condurache D-G. et al, (2023), Front Cardiovasc Med, 10
-
Efficacy and Tolerability of AXA1125, an Endogenous Metabolic Modulator Composition, in Fatigue-predominant Long COVID: A Randomized, Double-blind, Placebo-controlled Study
Conference paper
Finnigan L. et al, (2023), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207
-
IMPAIRED STRESS MYOCARDIAL OXYGENATION PRECEDES CONTRACTILE ABNORMALITIES IN THREE MODELS OF CARDIAC HYPERTROPHY: INSIGHTS FROM A NOVEL OXYGEN SENSITIVE CARDIAC MAGNETIC RESONANCE APPROACH
Conference paper
Akhtar MA. et al, (2023), HEART, 109, A8 - A9
-
LIVER DISEASE ACTIVITY IS A SIGNIFICANT RISK FACTOR FOR CARDIOVASCULAR OUTCOMES -A PROSPECTIVE ANALYSIS OF 33,616 INDIVIDUALS FROM THE UK BIOBANK
Conference paper
Roca-Fernandez A. et al, (2023), GASTROENTEROLOGY, 164, S72 - S73
-
Myocardial structure and function assessed by cardiac magnetic resonance in adolescents with perinatal-acquired HIV infection taking antiretroviral therapy
Conference paper
Majonga E. et al, (2023), BMJ GLOBAL HEALTH, 8, A7 - A7
-
Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank.
Journal article
Raisi-Estabragh Z. et al, (2022), Heart, 109, 119 - 126
-
Altered lung physiology in two cohorts post COVID-19 infection as assessed using computed cardiopulmonography.
Journal article
Magor-Elliott SRM. et al, (2022), J Appl Physiol (1985)
-
Role of Trientine in Hypertrophic Cardiomyopathy: A Review of Mechanistic Aspects.
Journal article
Ramli FF. et al, (2022), Pharmaceuticals (Basel), 15
-
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.
Journal article
PHOSP-COVID Collaborative Group None., (2022), Lancet Respir Med, 10, 761 - 775
-
Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses
Journal article
TOPIWALA A. et al, (2022), PLoS Medicine, 19
-
Right ventricular function declines prior to left ventricular ejection fraction in hypertrophic cardiomyopathy.
Journal article
Mahmod M. et al, (2022), J Cardiovasc Magn Reson, 24
-
Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19.
Journal article
Houchen-Wolloff L. et al, (2022), Thorax
-
Postpartum blood pressure self-management following hypertensive pregnancy: protocol of the Physician Optimised Post-partum Hypertension Treatment (POP-HT) trial.
Journal article
Kitt J. et al, (2022), BMJ Open, 12
-
Post-Vaccine Myocarditis: A Risk Worth the Reward?
Journal article
Raman B. and Neubauer S., (2022), Radiology
-
Long COVID / Post-Acute Sequelae of COVID-19 (PASC) with a cardiovascular focus
Journal article
RAMAN B. et al, (2022), European Heart Journal
-
ASSOCIATION OF MRI-DERIVED LIVER BIOMARKERS WITH CARDIOVASCULAR RISK FACTORS, OUTCOMES, AND ALL-CAUSE MORTALITY-A PROSPECTIVE ANALYSIS OF 33,616 INDIVIDUALS FROM THE UK BIOBANK COHORT
Conference paper
Roca-Fernandez A. et al, (2022), HEPATOLOGY, 76, S727 - S728
-
Cardiopulmonary Assessment of COVID-19 Survivors Stratified by Acute Disease Severity and Post-Acute Symptoms
Conference paper
Szekely Y. et al, (2022), CIRCULATION, 146
-
Comprehensive clinical assessment identifies specific neurocognitive deficits in working-age patients with long-COVID.
Journal article
Holdsworth DA. et al, (2022), PLoS One, 17
-
Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function.
Journal article
Ashkir Z. et al, (2022), Front Cardiovasc Med, 9
-
NOVEL INSIGHTS INTO DIMINISHED CARDIAC RESERVE IN HYPERTROPHIC CARDIOMYOPATHY FROM 4D FLOW CMR COMPONENT ANALYSIS
Conference paper
Ashkir Z. et al, (2022), HEART, 108, A3 - A4
-
Persistence of inflammatory and vascular damage mediators 5 months after acute COVID-19
Conference paper
Petousi N. et al, (2022), EUROPEAN RESPIRATORY JOURNAL, 60
-
The effects of sleep disturbance on dyspnoea and impaired lung function following COVID-19 hospitalisation: a prospective multi-centre cohort study
Preprint
Jackson C. et al, (2022)
-
Long-term clinical outcomes in patients with a working diagnosis of myocardial infarction with non-obstructed coronary arteries (MINOCA) assessed by cardiovascular magnetic resonance imaging.
Journal article
Ananthakrishna R. et al, (2021), Int J Cardiol
-
Association Between Sarcomeric Variants in Hypertrophic Cardiomyopathy and Myocardial Oxygenation: Insights From a Novel Oxygen-Sensitive Cardiovascular Magnetic Resonance Approach.
Journal article
Raman B. et al, (2021), Circulation, 144, 1656 - 1658
-
HEALTHIER CMR PHENOTYPES ARE LINKED TO FAVOURABLE BRAIN MRI STRUCTURE AND FUNCTION METRICS IN THE UK BIOBANK
Conference paper
McCracken C. et al, (2021), HEART, 107, A4 - A5
-
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Journal article
Evans RA. et al, (2021), Lancet Respir Med, 9, 1275 - 1287
-
Symptom Persistence Despite Improvement in Cardiopulmonary Health - Insights from longitudinal CMR, CPET and lung function testing post-COVID-19.
Journal article
Cassar MP. et al, (2021), EClinicalMedicine
-
Hyperpolarized 129Xe MRI Abnormalities in Dyspneic Patients 3 Months after COVID-19 Pneumonia: Preliminary Results.
Journal article
Grist JT. et al, (2021), Radiology, 301, E353 - E360
-
Longitudinal trajectory of cardiac magnetic resonance and cardiopulmonary exercise testing findings in moderate to severe COVID-19 and association with symptoms
Conference paper
Cassar MP. et al, (2021), EUROPEAN HEART JOURNAL, 42, 238 - 238
-
Late Breaking Abstract - Breathlessness post COVID-19 despite improvement in cardiopulmonary health
Conference paper
Cassar MP. et al, (2021), EUROPEAN RESPIRATORY JOURNAL, 58
-
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Journal article
Skelly DT. et al, (2021), Nat Commun, 12
-
Association of Preterm Birth with Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood
Journal article
LEWANDOWSKI A. et al, (2021), Journal of the American College of Cardiology
-
Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank.
Journal article
Raisi-Estabragh Z. et al, (2021), Aging Clin Exp Res, 33, 1133 - 1144
-
Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
Journal article
SHANMUGANATHAN M., (2021), EClinicalMedicine
-
Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
Journal article
Raman B. et al, (2021), EClinicalMedicine
-
Adapting the UK Biobank Brain Imaging Protocol and Analysis Pipeline for the C-MORE Multi-Organ Study of COVID-19 Survivors.
Journal article
Griffanti L. et al, (2021), Front Neurol, 12
-
Adapting the UK Biobank Brain Imaging Protocol and Analysis Pipeline for the C-MORE Multi-Organ Study of COVID-19 Survivors.
Journal article
Griffanti L. et al, (2021), Front Neurol, 12
-
Myocardial Deformation Analysis in Hypertrophic Cardiomyopathy With Sarcomere Mutations: Insights From 2,221 Patients Within the NHLBI-HCM Registry
Conference paper
Heydari B. et al, (2020), CIRCULATION, 142
-
Predicting the Future From Scars of the Past.
Journal article
Raman B. and Kramer CM., (2020), JACC Cardiovasc Imaging
-
Development of Therapeutic Strategies for Takotsubo Syndrome: Insights From a Rat Model
Conference paper
Surikow SY. et al, (2017), CIRCULATION, 136
-
Can Perhexiline Be Utilized Without Long-Term Toxicity? A Clinical Practice Audit
Journal article
Phuong H. et al, (2016), Therapeutic Drug Monitoring, 38, 73 - 78
-
Nitric Oxide Plays a Janus Role in the Pathogenesis of Tako-tsubo Cardiomyopathy
Conference paper
Nguyen TH. et al, (2015), CIRCULATION, 132
-
Determinants of shock and mortality in Takotsubo cardiomyopathy: a cohort study
Conference paper
Chong C-R. et al, (2015), EUROPEAN HEART JOURNAL, 36, 1177 - 1178
-
Troponin positive patients with unobstructed coronaries: incremental value of cardiovascular magnetic resonance
Conference paper
Raman B. et al, (2015), EUROPEAN HEART JOURNAL, 36, 380 - 380
-
Relation of delayed recovery of myocardial function after takotsubo cardiomyopathy to subsequent quality of life
Journal article
Neil CJ. et al, (2015), American Journal of Cardiology, 115, 1085 - 1089
-
Recurrent pulmonary oedema after percutaneous radiofrequency renal denervation
Journal article
Raman B. et al, (2014), International Journal of Cardiology, 174
-
Clopidogrel "resistance": Pre- vs post-receptor determinants
Journal article
Hurst NL. et al, (2013), Vascular Pharmacology, 59, 152 - 161
-
Not such a rarity: takotsubo cardiomyopathy as a mimic of ST elevation myocardial infarction
Conference paper
Raman B. et al, (2013), EUROPEAN HEART JOURNAL, 34, 539 - 539
-
Stress cardiomyopathy: new clinical and pathogenetic insights
Conference paper
Horowitz JD. et al, (2013), CARDIOLOGY, 126, 403 - 403