portrait
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Websites
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Sky news
Findings from the C-MORE - multiorgan MRI Study
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BBC news
Findings from the C-MORE - multiorgan MRI Study
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BBC world radio
Betty Raman presenting findings from the C-MORE study (8:20)
Betty Raman
MBBS DPhil FESC FRACP
Associate Professor of Cardiovascular Medicine
- Wellcome Career Development Award Fellow
- RDM Cardiovascular Medicine EDI Champion
I am an academic cardiologist and a senior clinical research fellow with a special interest in advanced cardiovascular magnetic resonance (CMR) and its applications to inherited cardiovascular diseases.
I moved from Australia to Oxford in 2015, having completed my specialist clinical training in Cardiology (Fellow of the Royal Australasian College of Physicians) to undertake a DPhil in Hypertrophic Cardiomyopathy (HCM), an inherited cardiac disease which is the number one cause of sudden death in young adults and athletes. During my DPhil, we discovered a novel oxygen-sensitive magnetic resonance approach, which showed tremendous potential in predicting risk in HCM patients and has the ability to detect myocardial deoxygenation/hypoxia in other diseases non-invasively (and without contrast). This work and other research of mine were recognised for their novelty and awarded a number of prestigious national and international prizes (ESC, AHA, BSCMR young investigator/early career awards, finalists at BCS and SCMR). For my post-doc, I was awarded a British Heart Foundation CRE Transition Intermediate Clinical Research Fellowship in 2020 to carry on my research. in HCM . At the peak of the pandemic, I also led efforts to better understand the medium to long term effects of COVID-19 on the health of patients using MRI, CPET and other validated measures of mental, physical and cognitive health in a large multicentre study (C-MORE study).
As part of my current research focus in HCM, I seek to identify early sensitive markers of disease activity for early- and late-stage clinical trials and for prognostic risk stratification. In 2024, I was awarded the highly prestigious Wellcome Career Development Award to discover and validate novel sensitive measures of disease activity in early stage HCM and to identify individuals at risk of disease progression and poor clinical outcomes. My research focusing on early-stage HCM using cutting-edge CMR measures, holds the potential to significantly improve the management of this disease. By precisely characterising patients at an unprecedented level of detail, I hope to proactively identify those poised for disease progression, thus enabling timely interventions with novel disease modifying and gene therapies. Dynamic endpoints that detect rapid response will not only minimise prolonged exposure to uncharted therapies but also pave the way for swift therapeutic assessments. My research is also expected to significantly accelerate the transition of drugs from phase II to phase III trials, fostering patient confidence and participation in these crucial studies.
Recent publications
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Journal article
McCracken C. et al, (2024), BMC Medicine, 22
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Journal article
Tyrer F. et al, (2024), Diabetes Obes Metab
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Journal article
Rua C. et al, (2024), Brain
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Journal article
Leavy OC. et al, (2024), ERJ Open Res, 10
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Journal article
Samat AHA. et al, (2024), Int J Cardiol, 415
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Journal article
Mahmod M. et al, (2024), Circ Cardiovasc Imaging, 17
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Journal article
Reddy SA. et al, (2024), Eur Respir J
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Journal article
Siontis KC. et al, (2024), Eur Heart J Digit Health, 5, 416 - 426
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Journal article
Coleman JA. et al, (2024), Cardiovascular research, cvae086 - cvae086
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Journal article
Coleman JA. et al, (2024), Frontiers in pharmacology, 15, 1379236 - 1379236
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Journal article
Liew F. et al, (2024), Nat Immunol, 25, 607 - 621
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Journal article
Devine K. et al, (2024), Clin Endocrinol (Oxf), 100, 317 - 327
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Journal article
Taquet M. et al, (2024), Brain Commun, 6
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Journal article
Singh SJ. et al, (2023), Eur Respir Rev, 32
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Journal article
Coleman J. et al, (2023), Computers in Biology and Medicine
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Journal article
Raman B. and Ramasamy MN., (2023), Lancet Infect Dis
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Journal article
Brightling CE. et al, (2023), Lancet Respir Med, 11, e93 - e94
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Journal article
C-MORE/PHOSP-COVID Collaborative Group None., (2023), Lancet Respir Med, 11, 1003 - 1019
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Journal article
Raman B., (2023), JACC Cardiovasc Imaging
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Journal article
Grist JT. et al, (2023), Radiology, 309
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Journal article
Taquet M. et al, (2023), Nat Med
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Journal article
Farrant J. et al, (2023), Heart, 109, 1175 - 1182
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Journal article
Coleman JA. et al, (2023), International Journal of Cardiovascular Imaging, 1 - 18
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Journal article
Roca-Fernandez A. et al, (2023), J Hepatol
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Journal article
Zheng B. et al, (2023), Lancet Reg Health Eur, 29
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Journal article
Hundertmark MJ. et al, (2023), Circulation, 147, 1654 - 1669
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Preprint
Elneima O. et al, (2023)
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Journal article
Finnigan LEM. et al, (2023), EClinicalMedicine, 59
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Journal article
Ashkir Z. et al, (2023), Eur Heart J Cardiovasc Imaging
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Journal article
Jackson C. et al, (2023), Lancet Respir Med
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Journal article
Heydari B. et al, (2023), JACC Cardiovasc Imaging, 16, 478 - 491
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Journal article
Shanmuganathan M. et al, (2023), Front Cardiovasc Med, 10
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Journal article
Daines L. et al, (2023), ERJ Open Res, 9
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Journal article
Condurache D-G. et al, (2023), Front Cardiovasc Med, 10
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Journal article
Raisi-Estabragh Z. et al, (2022), Heart, 109, 119 - 126
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Journal article
Magor-Elliott SRM. et al, (2022), J Appl Physiol (1985)
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Journal article
Ramli FF. et al, (2022), Pharmaceuticals (Basel), 15
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Journal article
PHOSP-COVID Collaborative Group None., (2022), Lancet Respir Med, 10, 761 - 775
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Journal article
TOPIWALA A. et al, (2022), PLoS Medicine, 19
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Journal article
Mahmod M. et al, (2022), J Cardiovasc Magn Reson, 24
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Journal article
Houchen-Wolloff L. et al, (2022), Thorax
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Journal article
Kitt J. et al, (2022), BMJ Open, 12
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Journal article
Raman B. and Neubauer S., (2022), Radiology
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Long COVID / Post-Acute Sequelae of COVID-19 (PASC) with a cardiovascular focus
Journal article
RAMAN B. et al, (2022), European Heart Journal
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Journal article
Holdsworth DA. et al, (2022), PLoS One, 17
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Journal article
Ashkir Z. et al, (2022), Front Cardiovasc Med, 9
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Preprint
Jackson C. et al, (2022)
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Journal article
Ananthakrishna R. et al, (2021), Int J Cardiol
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Journal article
Raman B. et al, (2021), Circulation, 144, 1656 - 1658
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Conference paper
McCracken C. et al, (2021), HEART, 107, A4 - A5
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Journal article
Evans RA. et al, (2021), Lancet Respir Med, 9, 1275 - 1287
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Journal article
Cassar MP. et al, (2021), EClinicalMedicine
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Journal article
Grist JT. et al, (2021), Radiology, 301, E353 - E360
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Longitudinal trajectory of cardiac magnetic resonance and cardiopulmonary exercise testing findings in moderate to severe COVID-19 and association with symptoms
Conference paper
Cassar MP. et al, (2021), EUROPEAN HEART JOURNAL, 42, 238 - 238
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Conference paper
Cassar MP. et al, (2021), EUROPEAN RESPIRATORY JOURNAL, 58
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Journal article
Skelly DT. et al, (2021), Nat Commun, 12
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Association of Preterm Birth with Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood
Journal article
LEWANDOWSKI A. et al, (2021), Journal of the American College of Cardiology
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Journal article
Raisi-Estabragh Z. et al, (2021), Aging Clin Exp Res, 33, 1133 - 1144
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Journal article
SHANMUGANATHAN M., (2021), EClinicalMedicine
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Journal article
Raman B. et al, (2021), EClinicalMedicine
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Journal article
Griffanti L. et al, (2021), Front Neurol, 12
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Journal article
Griffanti L. et al, (2021), Front Neurol, 12
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Conference paper
Heydari B. et al, (2020), CIRCULATION, 142
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Journal article
Raman B. and Kramer CM., (2020), JACC Cardiovasc Imaging
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Development of Therapeutic Strategies for Takotsubo Syndrome: Insights From a Rat Model
Conference paper
Surikow SY. et al, (2017), CIRCULATION, 136
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Journal article
Phuong H. et al, (2016), Therapeutic Drug Monitoring, 38, 73 - 78
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Nitric Oxide Plays a Janus Role in the Pathogenesis of Tako-tsubo Cardiomyopathy
Conference paper
Nguyen TH. et al, (2015), CIRCULATION, 132
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Determinants of shock and mortality in Takotsubo cardiomyopathy: a cohort study
Conference paper
Chong C-R. et al, (2015), EUROPEAN HEART JOURNAL, 36, 1177 - 1178
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Troponin positive patients with unobstructed coronaries: incremental value of cardiovascular magnetic resonance
Conference paper
Raman B. et al, (2015), EUROPEAN HEART JOURNAL, 36, 380 - 380
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Journal article
Neil CJ. et al, (2015), American Journal of Cardiology, 115, 1085 - 1089
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Journal article
Raman B. et al, (2014), International Journal of Cardiology, 174
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Journal article
Hurst NL. et al, (2013), Vascular Pharmacology, 59, 152 - 161
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Not such a rarity: takotsubo cardiomyopathy as a mimic of ST elevation myocardial infarction
Conference paper
Raman B. et al, (2013), EUROPEAN HEART JOURNAL, 34, 539 - 539
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Stress cardiomyopathy: new clinical and pathogenetic insights
Conference paper
Horowitz JD. et al, (2013), CARDIOLOGY, 126, 403 - 403