BHF CRE Graduate Student
Project: Myocardial labile iron handling and response to intravenous iron therapy
Supervisors: Associate Professor Samira Lakhal-Littleton, Dr Nick Talbot
I spent a year working with the Lakhal-Littleton Group as part of the Final Honour School in Medical Sciences while reading Pre-clinical Medicine at Brasenose College. We investigated the differential uptake of iron into atrial and ventricular cardiomyocytes, in response to intravenous iron treatment and haemochromatosis, and identified patterns of expression of iron homeostasis genes in the myocardium which could account for these differences.
I am now reading for an intercalated DPhil, affiliated with Exeter College, to further some of this work before continuing with clinical school. I am interested in ferric carboxymaltose, an intravenous iron therapy for the treatment of iron deficiency (increasingly in medical therapy for cardiovascular comorbidities, notably heart failure), and its effects on cardiac function. This work is funded by a British Heart Foundation Graduate Studentship and the Department of Physiology, Anatomy and Genetics.
Undergraduate degree: Pre-Clinical Medicine at the University of Oxford
Studentship dates: 2023-2026