Gil McVean
FRS FMedSci
Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Recent publications
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Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade
Journal article
KAUR G. et al, (2022), Nature Communications
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Recommendations for improving statistical inference in population genomics.
Journal article
Johri P. et al, (2022), PLoS Biol, 20
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Identification of host-pathogen-disease relationships using a scalable Multiplex Serology platform in UK Biobank
Journal article
MENTZER A. et al, (2022), Nature Communications
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A unified genealogy of modern and ancient genomes
Journal article
WONG HY. et al, (2022), Science
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Topic modelling with ICD10-informed priors identifies novel genetic loci associated with multimorbidities in UK Biobank
Preprint
Zhang Y. et al, (2022)