Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dr Kerstin N Timm

Oxford BHF CRE Basic Science Intermediate Transition Fellow

  • Start Date: 15/05/2020
  • End Date: 14/05/2022
  • BHF CRE Mentors: Prof Damian Tyler & Prof Antony Galione

Research project title: Cardioprotection in Doxorubicin-induced Heart Failure

Research summary:

Some chemotherapeutic agents, such as doxorubicin, have severe cardiotoxic side effects, which can lead to congestive heart failure in 5% of patients. There are currently no imaging techniques available to detect patients before the onset of functional decline and there are no specific cardio-protective drugs. My research focuses on both the early detection of cardiotoxicity using the novel metabolic imaging technique, hyperpolarized magnetic resonance imaging (MRI) and the repurposing of existing drugs that target cardiac metabolism as potential cardio-protective therapy.

Kerstin Timm Research Image.png

Biography:

As the number of cancer survivors increase, so do the unfortunate long-term side effects of chemotherapy. With my research, I hope to uncover imaging biomarkers that can identify early toxic changes to the heart in a preclinical setting. I furthermore hope to test existing drugs as cardioprotective agents in this setting, which could be repurposed in cancer patients to reduce the incidence of chemotherapy-induced heart failure.

I am excited to start my own independent research program as Career Development Fellow at the Department of Pharmacology. I hope to be able to secure an external Intermediate Level Fellowship in the next few years to drive my research in cardio-oncology forward. 

Undergraduate Degrees/Training:

Veterinary Medicine (FU Berlin, Germany)

MRes “In vivo imaging in Biology and Medicine” (Cambridge)