Contact information
robin.choudhury@cardiov.ox.ac.uk
+44 (0)1865 234664
Miss Eunice Berry
eunice.berry@cardiov.ox.ac.uk
Colleges
DPHIL SUPERVISOR PROFILE
Robin Choudhury
DM FRCP
Professor of Cardiovascular Medicine
- Honorary Consultant Cardiologist
- Clinical Director of AVIC
Integrative Physiology (Systems Biology)
This translational science laboratory aims to understand the functionally important heterogeneity in human cardiovascular disease to allow stratification of pathology and enable targeted therapies. Robin Choudhury qualified in medicine at the University of Oxford with postgraduate training in London (Royal Brompton & Hammersmith) and Oxford . At Mount Sinai School of Medicine, New York, he worked on lipoproteins and vascular inflammation and on developing MRI to characterize atherosclerosis.
He is currently Professor of Cardiovascular Medicine at the University of Oxford; Consultant Cardiologist at the John Radcliffe Hospital and Clinical Director of the Oxford Acute Vascular Imaging Centre and Research Fellow in Biomedical Sciences at Balliol.
His research interests focus on:
1) Understanding the role of monocytes and macrophages in acute MI, myocardial regeneration and atherosclerosis and how these cells are 'programmed' through by genetic / epigenetic and metabolic mechanisms.
2) How extracellular vesicles and their cargo signal tissue injury and programme cells of the innate immune system.
He is PI of the NovoNordisk Foundation Tripartite Immuno-metabolism Consortium (TrIC).
He serves on the Editorial Board of the Journal of the American Journal of Cardiology (Section Editor, Clinical Cardiology).
Key publications
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Inflammatory processes in cardiovascular disease: a route to targeted therapies.
Journal article
Ruparelia N. et al, (2017), Nat Rev Cardiol, 14, 133 - 144
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Arterial effects of canakinumab in patients with atherosclerosis and type 2 diabetes or glucose intolerance
Journal article
Choudhury RP. et al, (2016), Journal of the American College of Cardiology, 68, 1769 - 1780
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Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans.
Journal article
Ruparelia N. et al, (2015), Eur Heart J, 36, 1923 - 1934
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Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction.
Journal article
Akbar N. et al, (2017), JCI insight, 2
Recent publications
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Journal article
Kalla M. et al, (2020), Eur Heart J, 41, 2168 - 2179
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Journal article
De Maria GL. et al, (2020), Physiological measurement
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Journal article
Azzimato V. et al, (2020), Sci Transl Med, 12
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Journal article
Alkhalil M. et al, (2020), J Cardiovasc Magn Reson, 22, 3 - 3
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Journal article
Ruparelia N. and Choudhury R., (2020), Heart, 106, 80 - 85