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Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators.

Journal article

Chatzopoulou M. et al, (2020), ACS Med Chem Lett, 11, 2421 - 2427

Combining experimental strategies for successful target deconvolution.

Journal article

Wilkinson IVL. et al, (2020), Drug Discov Today

Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family.

Journal article

Quevedo CE. et al, (2020), Bioorg Med Chem, 28

Molecular Mechanism of Modulation of the TMEM16A Channel by Anthracene-9-Carboxylic Acid: Implications for Channel Gating

Conference paper

Dinsdale R. et al, (2020), BIOPHYSICAL JOURNAL, 118, 325A - 325A

Anthelmintic drug discovery: target identification, screening methods and the role of open science.

Journal article

Partridge FA. et al, (2020), Beilstein journal of organic chemistry, 16, 1203 - 1224

Target identification studies of a utrophin modulator for treatment of Duchenne muscular dystrophy

Conference paper

Wilkinson I. et al, (2019), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 257

Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Journal article

Cruz-Migoni A. et al, (2019), Proceedings of the National Academy of Sciences of the United States of America

Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.

Journal article

Stefaniak J. et al, (2018), ACS chemical biology

Small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy (DMD)

Conference paper

Russell A. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256

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