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Publications

Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution 31P-CMRS in the mouse.

Maguire ML. et al, (2023), J Cardiovasc Magn Reson, 25

Insights Into the Metabolic Aspects of Aortic Stenosis With the Use of Magnetic Resonance Imaging.

Monga S. et al, (2022), JACC Cardiovasc Imaging, 15, 2112 - 2126

Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure.

McAndrew DJ. et al, (2022), ESC Heart Fail

The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function.

Nitz K. et al, (2022), Circ Res

Oxidation of mitochondrial creatine kinase in hypertrophic cardiomyopathy facilitates ROS formation and premature permeability transition pore opening through loss of its chaperone function

Xu A. et al, (2022), EUROPEAN JOURNAL OF HEART FAILURE, 24, 10 - 10

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse.

Lygate CA. et al, (2022), Front Nutr, 9

Assessing Myocardial Microstructure with Biophysical Models of Diffusion MRI.

Farzi M. et al, (2021), IEEE Trans Med Imaging, PP

The Pitfalls of in vivo Cardiac Physiology in Genetically Modified Mice – Lessons Learnt the Hard Way in the Creatine Kinase System

Lygate CA., (2021), Frontiers in Physiology, 12

Altered calcium handling in cardiomyocytes from arginine-glycine amidinotransferase-knockout mice is rescued by creatine.

Laasmaa M. et al, (2021), American journal of physiology. Heart and circulatory physiology, 320, H805 - H825

Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency.

Branovets J. et al, (2021), American journal of physiology. Heart and circulatory physiology, 320, H613 - H629

BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes.

Carnicer Hijazo R. et al, (2021), Circulation research

Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.

Zervou S. et al, (2021), Front Physiol, 12

Cardiac Energetics in Patients with Aortic Stenosis and Preserved versus Reduced Ejection Fraction

Peterzan MA. et al, (2020), Circulation

SCREENING FOR SMALL MOLECULE REGULATORS OF THE CREATINE TRANSPORTER (SLC6A8)

Zervou S. et al, (2020), CARDIOVASCULAR DRUGS AND THERAPY, 34, 284 - 285

Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure

Cao F. et al, (2020), Basic Research in Cardiology, 115

Determinants of left ventricular ATP availability measured in vivo and ex vivo in patients with severe aortic stenosis: correlation of creatine kinase activity with LVEF and ATP diffusion distance

Peterzan MA. et al, (2019), EUROPEAN HEART JOURNAL, 40, 1338 - 1338

Non-invasive predictors of LV biopsy-obtained creatine kinase activity in patients with non-failing and failing myocardial hypertrophy

Peterzan MA. et al, (2019), EUROPEAN HEART JOURNAL, 40, 913 - 913

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A. et al, (2019), Mol Cancer Res, 17, 1531 - 1544

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T

CLARKE W. et al, (2019), NMR in Biomedicine

Age-Dependent Decline in Cardiac Function in Guanidinoacetate-N-Methyltransferase Knockout Mice.

Aksentijević D. et al, (2019), Front Physiol, 10

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