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Publications

Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.

Mattis KK. et al, (2023), Diabetologia

Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development.

Zhao J. et al, (2022), J Am Heart Assoc, 11

A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.

Issler N. et al, (2022), J Am Soc Nephrol

Altering the binding properties of PRDM9 partially restores fertility across the species boundary

DAVIES B., (2021), Molecular Biology and Evolution

Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia.

Jatho A. et al, (2021), Circ Res, 128, 1208 - 1210

When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping.

Sailer S. et al, (2021), Cell Biosci, 11

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

Sachse G. et al, (2021), Wellcome Open Research, 5, 15 - 15

Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages.

Navarro-Guerrero E. et al, (2021), Sci Rep, 11

Base editing and prime editing in laboratory animals

DAVIES B. and Caso F., (2021), Laboratory Animals

Functional analysis of a gene-edited mouse to gain insights into the disease mechanisms of a titin missense variant

JIANG H. et al, (2021), Basic Research in Cardiology

Replacement of surgical vasectomy through the use of wild-type sterile hybrids

Preece C. et al, (2021), Lab Animal

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.

Castroflorio E. et al, (2020), Cell Mol Life Sci

Fluorescent PSC-Derived Cardiomyocyte Reporter Lines: Generation Approaches and Their Applications in Cardiovascular Medicine.

Sontayananon N. et al, (2020), Biology (Basel), 9

Electroporation and genetic supply of Cas9 increase the generation efficiency of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes

DAVIES B., (2020), Scientific Reports

Electroporation and genetic supply of Cas9 increase the generation efficiency of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes

DAVIES B., (2020), Scientific Reports

Regulation of substrate choice contributes to the regulation of glucagon secretion from alpha cells in response to glucose

Armour SL. et al, (2020), DIABETOLOGIA, 63, S70 - S71

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.

Hinch AG. et al, (2020), Mol Cell

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

Sachse G. et al, (2020), Wellcome Open Research, 5, 15 - 15

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.

Dwivedi OP. et al, (2019), Nat Genet

Genetic diversity and its unexpected impacts on recombination, genome evolution, speciation and sterility in mammals

Li R. et al, (2019), EUROPEAN JOURNAL OF HUMAN GENETICS, 27, 1073 - 1073

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