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Publications

Exogenous d-β-hydroxybutyrate lowers blood glucose in part by decreasing the availability of L-alanine for gluconeogenesis.

Soto-Mota A. et al, (2021), Endocrinol Diabetes Metab

Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia.

Kerr M. et al, (2021), FASEB J, 35

Metabolic maturation of differentiating cardiosphere-derived cells.

Pakzad KK. et al, (2021), Stem Cell Res, 54

The Effect of Blood Ketone Concentration and Exercise Intensity on Exogenous Ketone Oxidation Rates in Athletes.

Dearlove DJ. et al, (2021), Med Sci Sports Exerc, 53, 505 - 516

Effects of acute nutritional ketosis during exercise in adults with glycogen storage disease type IIIa are phenotype-specific: An investigator-initiated, randomized, crossover study.

Hoogeveen IJ. et al, (2021), J Inherit Metab Dis, 44, 226 - 239

Exogenous ketosis in patients with type 2 diabetes: Safety, tolerability and effect on glycaemic control

Soto-Mota A. et al, (2021), Endocrinology, Diabetes and Metabolism

The Use of Reactive Oxygen Species Production by Succinate-Driven Reverse Electron Flow as an Index of Complex 1 Activity in Isolated Brown Adipose Tissue Mitochondria

Dlasková A. et al, (2021), Methods in Molecular Biology, 2310, 247 - 258

The ketone ester, 3-hydroxybutyl-3-hydroxybutyrate, attenuates neurobehavioral deficits and improves neuropathology following controlled cortical impact in male rats.

Almeida-Suhett C. et al, (2020), Nutr Neurosci, 1 - 13

Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.

Watson WD. et al, (2020), FASEB J, 34, 14878 - 14891

Cardiac ketone body metabolism

Abdul Kadir A. et al, (2020), Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866

Diet modulates brain network stability, a biomarker for brain aging, in young adults.

Mujica-Parodi LR. et al, (2020), Proc Natl Acad Sci U S A, 117, 6170 - 6177

Why a d-β-hydroxybutyrate monoester?

Soto-Mota A. et al, (2020), Biochemical Society Transactions, 48, 51 - 59

Nutritional ketosis improves exercise metabolism in patients with very long-chain acyl-CoA dehydrogenase deficiency.

Bleeker JC. et al, (2020), J Inherit Metab Dis

A Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.

Norwitz NG. et al, (2020), Front Neurosci, 14

Ketotherapeutics for neurodegenerative diseases

Norwitz NG. et al, (2020), International Review of Neurobiology

Male sex adversely affects the phenotypic expression of diabetic heart disease

Athithan L. et al, (2020), Therapeutic Advances in Endocrinology and Metabolism, 11

A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: a randomized trial.

Myette-Côté É. et al, (2019), Am J Clin Nutr, 110, 1491 - 1501

Safety and tolerability of sustained exogenous ketosis using ketone monoester drinks for 28 days in healthy adults.

Soto-Mota A. et al, (2019), Regul Toxicol Pharmacol, 109

Context is key: exogenous ketosis and athletic performance

Dearlove DJ. et al, (2019), Current Opinion in Physiology, 10, 81 - 89

Gastrointestinal Effects of Exogenous Ketone Drinks are Infrequent, Mild and Vary According to Ketone Compound and Dose.

Stubbs BJ. et al, (2019), Int J Sport Nutr Exerc Metab, 1 - 23

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