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Publications

Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation

PLATT F., (2024), iScience

Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of its Pathology.

Heather LC. et al, (2024), Diabetes

CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease.

Glatz JFC. et al, (2023), Physiol Rev

Targeting mitochondrial oxidative phosphorylation: lessons, advantages, and opportunities.

Machado ND. et al, (2023), Br J Cancer, 129, 897 - 899

Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.

Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890

Post-translational palmitoylation of metabolic proteins.

Dennis KMJH. and Heather LC., (2023), Front Physiol, 14

Cardiometabolic risk factors vary with age differently in females and males

Miller JJ. and Heather LC., (2022), Nature Cardiovascular Research, 1, 796 - 797

Unravelling the role of acidic organelles in Goat Atrial Fibrillation

Ayagama T. et al, (2022), ACTA PHYSIOLOGICA, 236, 931 - 933

Guidelines on Models of Diabetic Heart Disease.

Heather LC. et al, (2022), Am J Physiol Heart Circ Physiol

Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.

Hazlehurst JM. et al, (2022), Metabol Open, 14

Deletion of tetrahydrobiopterin synthesis in cardiomyocytes causes downregulation of fatty acid metabolism whilst protected against cardiac ischemia reperfusion injury

Chu S. et al, (2022), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 173, S125 - S125

Human metabolism: pathways and clinical aspects

Evans RD. and Heather LC., (2022), Surgery (United Kingdom)

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.

da Luz Sousa Fialho M. et al, (2021), Diabetes

Peritransplant Cardiometabolic and Mitochondrial Function: The Missing Piece in Donor Heart Dysfunction and Graft Failure.

Wells MA. et al, (2021), Transplantation, 105, 496 - 508

Hyperpolarized magnetic resonance shows that the antiischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved postischemic function in the diabetic heart

SAVIC D. et al, (2021), NMR in Biomedicine

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

Timm KN. et al, (2020), Communications Biology, 3

Rapid, $B_1$-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

Miller JJ. et al, (2020), Magnetic Resonance in Medicine

Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus.

Faulkner A. et al, (2020), Diabetologia, 63, 2205 - 2217

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol.

Kerr M. et al, (2020), JCI Insight, 5

Positioning Metabolism as a Central Player in the Diabetic Heart.

Mereweather LJ. et al, (2020), J Lipid Atheroscler, 9, 92 - 109

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