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Publications

Cardiomyocyte electrophysiology and its modulation: current views and future prospects.

Huang CL-H. and Lei M., (2023), Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 378

Targeting p21-activated kinase 1 for development of a novel anti-arrhythmic drug class.

He Y. et al, (2023), Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 378

High resolution optical mapping of cardiac electrophysiology in pre-clinical models

O’Shea C. et al, (2022), Scientific Data, 9

Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling.

Luo X. et al, (2022), Oxid Med Cell Longev, 2022

High-Resolution 3D Heart Models of Cardiomyocyte Subpopulations in Cleared Murine Heart.

Ren H. et al, (2022), Front Physiol, 13

A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts

He S. et al, (2021), Scientific Data, 8

Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1.

Yang B. et al, (2021), J Mol Cell Cardiol

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca2+ and Mg2.

Wilson AD. et al, (2021), J Physiol

Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts.

Wang G. et al, (2021), ACS Pharmacol Transl Sci, 4, 1639 - 1653

Generation of induced pluripotent stem cells (iPSCs) from a Chinese infant (XACHi015-A) with type 2 Long QT syndrome carrying the heterozygous mutation c.1814C>T(p.P605L) in KCNH2.

Wang T. et al, (2021), Stem Cell Res, 56

Establishment of iPSC line from a Chinese infant (XACHi012-A) with Jervell and Lange-Nielsen syndrome carrying combined KCNQ1 frameshift c.431delC(p.I145Sfs*92) and nonsense c.1175G > A (p.W392X) variants and two iPSC lines from the parents (XACHi013-A, XACHi014-A).

Zhou Y. et al, (2021), Stem Cell Res, 53

A Comparative Study of Systolic and Diastolic Mechanical Synchrony in Canine, Primate, and Healthy and Failing Human Hearts.

Zhu T. et al, (2021), Front Cardiovasc Med, 8

Cardiac optical mapping - State-of-the-art and future challenges.

O'Shea C. et al, (2020), Int J Biochem Cell Biol, 126

Novel cardiac cell subpopulations: Pnmt-derived cardiomyocytes.

Grassam-Rowe A. et al, (2020), Open Biol, 10

Generation of two induced pluripotent stem cell lines (XACHi0010-A, XACHi0011-A) from a Chinese family with combined oxidative phosphorylation deficiency carrying homozygous and heterozygous C1QBP-L275F mutation.

Zhang Y. et al, (2020), Stem Cell Res, 47

Generation of three iPSC lines (XACHi007-A, XACHi008-A, XACHi009-A) from a Chinese family with long QT syndrome type 5 with heterozygous c.226G>A (p.D76N) mutation in KCNE1gene.

Zhang Y. et al, (2020), Stem Cell Res, 45

A new method of transverse cardiac slicing and optical mapping of murine heart

He S. et al, (2020), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 140, 10 - 11

Antiarrhythmic drugs - An updated classification after 50 years

Lei M. and Huang C., (2020), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 140, 10 - 10

Update on antiarrhythmic drug pharmacology.

Huang CL-H. et al, (2020), J Cardiovasc Electrophysiol, 31, 579 - 592

Editorial: Optogenetics: An Emerging Approach in Cardiac Electrophysiology.

Huang CL-H. et al, (2020), Front Physiol, 11

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