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Publications

How protons pave the way to aggressive cancers

SWIETACH P. et al, (2023), Nature Reviews Cancer

Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter Anion Exchanger 2 (SLC4A2)

MICHL J. et al, (2023), Cell Reports

Diffusion-limited O2release in human kidneys perfused with stored blood

Dumbill R. et al, (2023)

Permeability and driving force: why is difficult to control glycolytic flux by blocking lactate transporters?

Blaszczak W. and Swietach P., (2023), Oncotarget, 14, 51 - 52

Proton export upregulates aerobic glycolysis

Russell S. et al, (2022), BMC Biology, 20

Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes.

Monterisi S. et al, (2022), Elife, 11

Auto-regulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production

BLASZCZAK W. et al, (2022), British Journal of Cancer

Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells

Rabcuka J. et al, (2022), Blood Advances

Elevated propionate signalling drives Pde9a overexpression and contractile dysfunction through increased histone acetylation and propionylation

Park KC. et al, (2022), CARDIOVASCULAR RESEARCH, 118

Channelling protons out of the heart.

Swietach P. and Despa S., (2022), J Physiol

Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy

Pillai S. et al, (2022), Cell Reports, 39, 110796 - 110796

Optimal thinning of MCMC output

SWIETACH P., (2022), Journal- Royal Statistical Society Series B

Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes

Monterisi S. et al, (2022)

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

HULIKOVA A. et al, (2022), Basic Research in Cardiology

CRISPR/Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

MICHL J. et al, (2022), Cell Reports

Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH

Abigail W. et al, (2021), Cardiovascular Research

What do cellular responses to acidity tell us about cancer?

BLASZCZAK W. and SWIETACH P., (2021), Cancer and Metastasis Reviews

Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter

SWIETACH P. and DONOVAN K., (2021), Haematologica: the hematology journal

Cost-Effective Real-Time Metabolic Profiling of Cancer Cell Lines for Plate-Based Assays

Blaszczak W. et al, (2021), CHEMOSENSORS, 9, 139 - 139

Sulphamate Derivatives of Maslinic Acid as a Therapeutic Option for human Breast Cancer

Petrenko M. et al, (2021), STRAHLENTHERAPIE UND ONKOLOGIE, 197, S131 - S132

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