Development of a fluorescence-based assay for RecBCD activity using Functional Data Analysis and Design of Experiments
Winnifrith A. et al, (2025), RSC Chemical Biology
Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase.
Ritzefeld M. et al, (2024), J Med Chem, 67, 1061 - 1078
Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
Bradbury JD. et al, (2024), Chemical Science
Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Jamshidiha M. et al, (2022), RSC medicinal chemistry, 13, 150 - 155
Evaluating Hedgehog Acyltransferase Activity and Inhibition Using the Acylation-coupled Lipophilic Induction of Polarization (Acyl-cLIP) Assay.
Andrei SA. et al, (2022), 2374, 13 - 26
Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Coupland CE. et al, (2021), Mol Cell, 81, 5025 - 5038.e10
Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**
Lanyon‐Hogg T. et al, (2021), Angewandte Chemie, 133, 13654 - 13659
Correction to "Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity".
Panyain N. et al, (2020), Journal of the American Chemical Society, 142