Contact information
DPHIL SUPERVISOR PROFILE
Gillian Douglas
PhD
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
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Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma
Journal article
BISHOP T., (2021), Endocrine-Related Cancer
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Endothelial GTP Cyclohydrolase and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling and Fetal Growth
Journal article
CHUAIPHICHAI S. et al, (2021), Hypertension
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Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition
Journal article
AKOUMIANAKIS I. et al, (2020), Science Translational Medicine
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A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.
Journal article
Douglas G. et al, (2019), Cardiovasc Res
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Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17//RAC1-mediated activation of NADPH oxidases
Journal article
AKOUMIANAKIS I. et al, (2019), Science Translational Medicine