Contact information
Gillian Douglas
PhD
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
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Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
Journal article
Chu SM. et al, (2023), Exp Physiol
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Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
Journal article
Chuaiphichai S. et al, (2023), Vascul Pharmacol, 150
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Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2
Journal article
Broadway-Stringer S. et al, (2023), Cells
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Endothelial Cell-Specific Roles for Tetrahydrobiopterin in Myocardial Function, Cardiac Hypertrophy and Response to Myocardial Ischemia-Reperfusion Injury.
Journal article
Chuaiphichai S. et al, (2023), Am J Physiol Heart Circ Physiol
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Crucial functions of alpha-actinin 2 in the embryonic heart
Conference paper
Gehmlich K. et al, (2022), CARDIOVASCULAR RESEARCH, 118