Contact information
Gillian Douglas
PhD
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
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AnALPK3truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten
Preprint
Leinhos L. et al, (2024)
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A Novel Role of 5-Methyl-(6S)-tetrahydrofolate in Mediating Endothelial Cell Tetrahydrobiopterin in Pregnancy and Implications for Gestational Hypertension
Journal article
Dickinson Y. et al, (2024), Hypertension
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Hif-2α programmes oxygen chemosensitivity in chromaffin cells.
Journal article
Prange-Barczynska M. et al, (2024), J Clin Invest
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Mutagenesis on a complex mouse genetic background by site-specific nucleases.
Journal article
Davies B. et al, (2024), Transgenic Res
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Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
Journal article
Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890