Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

It is now well recognized that the atherosclerotic plaques responsible for thrombus formation are not necessarily those that impinge most on the lumen of the vessel. Nevertheless, clinical investigations for atherosclerosis still focus on quantifying the degree of stenosis caused by plaques. Many of the features associated with a high-risk plaque, including a thin fibrous cap, large necrotic core, macrophage infiltration, neovascularization, and intraplaque hemorrhage, can now be probed by novel imaging techniques. Each technique has its own strengths and drawbacks. In this article, we review the various imaging modalities used for the evaluation and quantification of atherosclerosis.

Original publication

DOI

10.1146/annurev-med-041709-133809

Type

Journal article

Journal

Annu Rev Med

Publication Date

2011

Volume

62

Pages

25 - 40

Keywords

Animals, Atherosclerosis, Carotid Artery Diseases, Carotid Stenosis, Constriction, Pathologic, Endothelium, Vascular, Female, Fluorodeoxyglucose F18, Humans, Magnetic Resonance Imaging, Male, Mice, Plaque, Atherosclerotic, Positron-Emission Tomography, Tomography, X-Ray Computed, Ultrasonography