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A number of vasoactive mediators have been identified in plasma and in the heart. Some of them may be liberated in inflammatory heart disease. The action of mediators on coronary vasculature in various animal models and their potential role in inflammatory heart disease is reviewed. Their role in patients remains to be determined.

Original publication




Journal article


Eur Heart J

Publication Date



12 Suppl D


187 - 189


Adrenal Glands, Animals, Atrial Natriuretic Factor, Cardiomyopathy, Dilated, Coronary Circulation, Coronary Vessels, Eicosanoids, Endothelium, Vascular, Humans, Myocarditis, Neuropeptides, Renin-Angiotensin System, Sympathetic Nervous System, Vasopressins