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An adolescent haemophiliac group (all less than 1 per cent Factor VIII) and a normal, similarly aged, 'control group' of boys were examined to measure joint laxity in an effort to identify a causative factor for bleeding. Definitive laxity was found in the thumb joints and in finger extension of haemophiliacs compared with normal boys. The haemophiliacs who were more lax-jointed showed no tendency towards an increased number of bleeds when they were followed for 100 days. Possible explanations for these phenomena are discussed.


Journal article



Publication Date





337 - 342


Adolescent, Adult, Ankle Joint, Child, Finger Joint, Hemophilia A, Hemorrhage, Humans, Joints, Male, Movement, Thumb