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The report in March 1996 of 10 human cases of a novel from of Creutzfeldt-Jakob disease in the United Kingdom, and its possible link to the agent that causes bovine spongiform encephalopathy (BSE), raises many questions about the safety of animal-derived products and by-products entering the food chain or being used in medicine. This Memorandum updates the preventive measures put forward in 1991 to minimize the risks associated with the use of bovine-derived materials in medicinal products and medical devices.


Conference paper

Publication Date





505 - 513


Adult, Animals, Biocompatible Materials, Blood Proteins, Cattle, Creutzfeldt-Jakob Syndrome, Encephalopathy, Bovine Spongiform, Food Microbiology, Humans, Milk, PrPC Proteins, Sheep, Zoonoses