Joaquim Miguel Vieira
BHF Intermediate Basic Science Research Fellow
I studied Biochemistry at the University of Lisbon, Portugal. Then, I moved to London for my PhD studies on the role of Neuropilin-1 and its ligands during blood vessel growth and patterning in Professor Christiana Ruhrberg's laboratory at University College London (UCL)-Institute of Ophthalmology.
In 2008, I started as a postdoctoral researcher at UCL-Institute of Child Health in Professor Paul Riley's laboratory to work on the characterisation of adult epicardium-derived cells (EPDCs) and their contribution to cardiovascular homeostasis and endogenous repair. In 2012, I moved to Oxford as a senior postdoctoral researcher in Professor Paul Riley's team and my research focus included the investigation of the epigenetic mechanisms controlling epicardial activity during heart development and disease; and characterisation of the cardiac lymphatic vasculature in the developing and diseased heart.
In 2019, I was awarded a British Heart Foundation (BHF) Intermediate Basic Science Research Fellowship to start my research group and study the functional role of the noncoding genome (long noncoding RNAs and enhancers) during epithelial-to-mesenchymal transition (EMT) in the developing and diseased heart. By creating a blueprint of noncoding sequences that influence EMT in the heart, it might be possible to enable cardiovascular regeneration.
October 2018 - September 2019: (non-stipendiary) Lecturer in Medicine at St. Hilda's College
October 2013 - October 2015: (non-stipendiary) Fulford Junior Research Fellow at Somerville College
Cahill TJ. et al, (2021), Development
The evolving cardiac lymphatic vasculature in development, repair and regeneration
VIEIRA J. et al, (2021), Nature Reviews Cardiology
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart
VIEIRA J. et al, (2021), Development
Price EL. et al, (2019), Disease models & mechanisms, 12