Websites
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British Heart Foundation
Funder
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NO Society
10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
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Nitric Oxide Society
Advancing basic and applied scientific research to fully realize the impact of Nitric Oxide on mankind.
Mark Crabtree
BSc (Hons), PhD
Visiting Scientist
- British Heart Foundation Intermediate Basic Science Research Fellow
Mark Crabtree is a British Heart Foundation Intermediate Basic Science Research Fellow and became a Group Leader and University Research Lecturer within the Division of Cardiovascular Medicine in 2015. His research group focuses on understanding the mechanisms of nitric oxide and redox signalling in molecular models of cardiovascular disease.
He began his postdoctoral research with Professor Keith Channon in 2006 and he held an internal University of Oxford British Heart Foundation Centre of Research Excellence Transition Fellowship (2012-2015). Mark did a collaborative PhD with the University of Surrey and Weill Medical College of Cornell University in New York City, having completed his BSc at the University of Surrey in 2001.
Mark is an active council member for the Nitric Oxide Society and is the meeting Chair for the International Nitric Oxide Society Conference being held in Oxford in in 2018.
His research interests focus on metabolomic and proteomic approaches to understand the impact of redox alterations in molecular and mouse models of cardiovascular homeostasis and disease.
Recent publications
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Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents.
Journal article
Tabish TA. et al, (2024), Applied physics reviews, 11, 5.0192379 - 5.0192379
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pH-sensitive release of nitric oxide gas using peptide-graphene co-assembled hybrid nanosheets.
Journal article
Tabish TA. et al, (2024), Nitric Oxide, 147, 42 - 50
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S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications.
Journal article
Tabish TA. et al, (2024), Redox Biol, 72
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Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
Journal article
Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890
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Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury.
Journal article
Chuaiphichai S. et al, (2023), Am J Physiol Heart Circ Physiol, 324, H430 - H442