Research groups
Colleges
Mathilda Mommersteeg
Associate Professor of Developmental and Regenerative Medicine
- Deputy Director of Graduate Studies
I obtained my PhD in 2009 from the University of Amsterdam, where I worked in the laboratories of Prof. Vincent Christoffels and Prof. Antoon Moorman on the development of the conduction system and venous pole of the mammalian heart. In 2010, I joined the laboratory of Prof. John Parnavelas at University College London (UCL) as a long-term EMBO fellow. At UCL, my work focused on deciphering the roles of the Slit-Robo signalling pathway during mammalian heart development. While at UCL, I set up a project researching heart regeneration in Mexican cavefish together with dr. Yoshiyuki Yamamoto, which was sponsored by the British Heart Foundation in 2012. Both my post-doctoral projects form the basis for my current research interests in investigating the molecular mechanisms underlying heart regeneration and development.
Recent publications
Assessing the Metabolic Activity of Whole Regenerating Zebrafish Ventricles Ex Vivo Using an Extracellular Flux Assay.
Journal article
Lekkos K. et al, (2026), J Vis Exp
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development.
Preprint
Zhao J. et al, (2025)
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development
Journal article
Zhao J. et al, (2025), eLife, 14
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development
Preprint
Zhao J. et al, (2025)
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration.
Journal article
Lekkos K. et al, (2025), Nat Cardiovasc Res, 4, 1363 - 1380