Yvonne Couch

Oxford BHF CRE Basic Science Intermediate Transition Fellow

Start date: 1st August 2024
End date: 31st July 2026
BHF CRE mentors: Prof. Damian Tyler & Prof. Heidi Johansen-Berg

Contact information

Project title: The longer-term metabolic consequences of stroke

Research summary

Traditional PET imaging of metabolic processes fails to give us the full picture of metabolic processing in tissue. The brain is an extremely metabolically active organ and understanding what happens to metabolism in the CNS, especially in injuries such as stroke, and in diseases such as dementia, is the long-term goal for this research.

Research image

This project will use models of stroke to determine changes in metabolic activity in the acute and chronic phases after injury. By using a combination of male and female and young and old animals, we hope to more accurately represent the patient population post-stroke.

I will continue to work with experts in post-stroke recovery and imaging (Profs. Johansen-Berg and Tyler) in order to make the most of this transitional fellowship with the ultimate aim of turning into a larger project studying metabolism from bench to bedside in post-stroke dementia in the future.