Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm.
Journal article
Loick P. et al, (2023), Arterioscler Thromb Vasc Biol
Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration.
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Liu Y. et al, (2022), Exp Eye Res, 218
The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload.
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Mohammad G. et al, (2021), Kidney International
fetal liver hepcidin secures iron stores in utero
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LAKHAL-LITTLETON S. et al, (2020), Blood
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing.
Journal article
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Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration.
Journal article
Baumann BH. et al, (2019), Am J Pathol, 189, 1814 - 1830
Iron Deficiency as a Therapeutic Target in Cardiovascular Disease.
Journal article
Lakhal-Littleton S., (2019), Pharmaceuticals (Basel), 12
IMPACTS OF MATERNAL IRON DEFICIENCY ON THE MOUSE PLACENTAL-HEART AXIS
Conference paper
Kalisch-Smith J. et al, (2019), PLACENTA, 83, E47 - E48
Ferroportin-mediated iron export from vascular endothelial cells in retina and brain.
Journal article
Baumann BH. et al, (2019), Exp Eye Res
Ferroportin promotes iron import through the retinal vascular endothelium
Conference paper
Shu W. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60
Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice
Journal article
LAKHAL-LITTLETON SAMIRA. et al, (2019), Proceedings of the National Academy of Sciences
IRON DEFICIENCY IN PULMONARY ARTERIAL SMOOTH MUSCLE CELLS INDUCES PULMONARY ARTERIAL HYPERTENSION THROUGH ENDOTHELIN-1
Conference paper
Lakhal-Littleton S. et al, (2019), HEART, 105, A142 - A143
Mechanisms of cardiac iron homeostasis and their importance to heart function.
Journal article
Lakhal-Littleton S., (2019), Free Radic Biol Med, 133, 234 - 237
Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity
Journal article
Chung Y. et al, (2019), JCI insight
Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload.
Journal article
Schwartz AJ. et al, (2019), J Clin Invest, 129, 336 - 348
Cardiomyocyte hepcidin: From intracellular iron homeostasis to physiological function.
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Hepatic hepcidin/intestinal HIF-2a axis maintains iron absorption during iron deficiency and overload
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LAKHAL-LITTLETON S., (2018), Journal of Clinical Investigation
THE INTERPLAY BETWEEN IRON AND OXYGEN HOMEOSTASIS WITH A PARTICULAR FOCUS ON THE HEART
Journal article
Lakhal-Littleton S. and Robbins PA., (2017), Journal of applied physiology (Bethesda, Md. : 1985), jap.00237.2017 - jap.00237.2017
LOSS OF LOCAL HEPCIDIN DECREASES TUMORIGENESIS IN COLORECTAL CANCER
Conference paper
Schwartz A. et al, (2017), AMERICAN JOURNAL OF HEMATOLOGY, 92, E211 - E211
Environmental influences on mouse embryonic heart development
Conference paper
Sparrow D. et al, (2017), MECHANISMS OF DEVELOPMENT, 145, S157 - S158