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Publications

Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm.

Loick P. et al, (2023), Arterioscler Thromb Vasc Biol

Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration.

Liu Y. et al, (2022), Exp Eye Res, 218

The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload.

Mohammad G. et al, (2021), Kidney International

fetal liver hepcidin secures iron stores in utero

LAKHAL-LITTLETON S. et al, (2020), Blood

Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing.

Bessman NJ. et al, (2020), Science, 368, 186 - 189

Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration.

Baumann BH. et al, (2019), Am J Pathol, 189, 1814 - 1830

Iron Deficiency as a Therapeutic Target in Cardiovascular Disease.

Lakhal-Littleton S., (2019), Pharmaceuticals (Basel), 12

IMPACTS OF MATERNAL IRON DEFICIENCY ON THE MOUSE PLACENTAL-HEART AXIS

Kalisch-Smith J. et al, (2019), PLACENTA, 83, E47 - E48

Ferroportin-mediated iron export from vascular endothelial cells in retina and brain.

Baumann BH. et al, (2019), Exp Eye Res

Ferroportin promotes iron import through the retinal vascular endothelium

Shu W. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice

LAKHAL-LITTLETON SAMIRA. et al, (2019), Proceedings of the National Academy of Sciences

IRON DEFICIENCY IN PULMONARY ARTERIAL SMOOTH MUSCLE CELLS INDUCES PULMONARY ARTERIAL HYPERTENSION THROUGH ENDOTHELIN-1

Lakhal-Littleton S. et al, (2019), HEART, 105, A142 - A143

Mechanisms of cardiac iron homeostasis and their importance to heart function.

Lakhal-Littleton S., (2019), Free Radic Biol Med, 133, 234 - 237

Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity

Chung Y. et al, (2019), JCI insight

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload.

Schwartz AJ. et al, (2019), J Clin Invest, 129, 336 - 348

Cardiomyocyte hepcidin: From intracellular iron homeostasis to physiological function.

Lakhal-Littleton S., (2019), 110, 189 - 200

Hepatic hepcidin/intestinal HIF-2a axis maintains iron absorption during iron deficiency and overload

LAKHAL-LITTLETON S., (2018), Journal of Clinical Investigation

THE INTERPLAY BETWEEN IRON AND OXYGEN HOMEOSTASIS WITH A PARTICULAR FOCUS ON THE HEART

Lakhal-Littleton S. and Robbins PA., (2017), Journal of applied physiology (Bethesda, Md. : 1985), jap.00237.2017 - jap.00237.2017

LOSS OF LOCAL HEPCIDIN DECREASES TUMORIGENESIS IN COLORECTAL CANCER

Schwartz A. et al, (2017), AMERICAN JOURNAL OF HEMATOLOGY, 92, E211 - E211

Environmental influences on mouse embryonic heart development

Sparrow D. et al, (2017), MECHANISMS OF DEVELOPMENT, 145, S157 - S158

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