Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure.
Journal article
McAndrew DJ. et al, (2022), ESC Heart Fail
Influence of homoarginine on creatine accumulation and biosynthesis in the mouse.
Journal article
Lygate CA. et al, (2022), Front Nutr, 9
Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart.
Journal article
Zervou S. et al, (2021), Front Physiol, 12
SCREENING FOR SMALL MOLECULE REGULATORS OF THE CREATINE TRANSPORTER (SLC6A8)
Conference paper
Zervou S. et al, (2020), CARDIOVASCULAR DRUGS AND THERAPY, 34, 284 - 285
Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure
Journal article
Cao F. et al, (2020), Basic Research in Cardiology, 115
Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.
Journal article
Valli A. et al, (2019), Mol Cancer Res, 17, 1531 - 1544
Age-Dependent Decline in Cardiac Function in Guanidinoacetate-N-Methyltransferase Knockout Mice.
Journal article
Aksentijević D. et al, (2019), Front Physiol, 10
The creatine kinase system as a therapeutic target for myocardial ischaemia-reperfusion injury.
Journal article
Cao F. et al, (2018), Biochem Soc Trans, 46, 1119 - 1127
Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia-reperfusion.
Journal article
Whittington HJ. et al, (2018), Cardiovasc Res, 114, 858 - 869
CROSSTALK BETWEEN GLUCOSE AND CREATINE IN THE HEART
Conference paper
Whittington HJ. et al, (2018), HEART, 104, A3 - A3
Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine.
Journal article
Faller KME. et al, (2017), Cardiovascular research
Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.
Journal article
Zervou S. et al, (2017), PLoS ONE, 12, e0182994 - e0182994
AUGMENTATION OF CREATINE KINASE IN VITRO PROTECTS AGAINST SIMULATED ISCHAEMIA REPERFUSION INJURY
Conference paper
Zervou S. et al, (2017), HEART, 103, A144 - A144
Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure.
Journal article
Atzler D. et al, (2017), Circulation, 135, 400 - 402
Augmentation of Creatine in the Heart.
Journal article
Zervou S. et al, (2016), Mini Rev Med Chem, 16, 19 - 28
Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms.
Journal article
Zervou S. et al, (2016), Amino acids, 48, 1969 - 1981
Augmentation of Creatine in the Heart.
Journal article
Zervou S. et al, (2016), Mini Rev Med Chem, 16, 19 - 28
Homoarginine Supplementation Improves Cardiac Function in a Murine Model of Ischaemic Heart Failure
Conference paper
Atzler D. et al, (2015), CIRCULATION, 132
LOSS OF HOMOARGININE IS RESPONSIBLE FOR CARDIAC DYSFUNCTION IN CREATINE-DEFICIENT ARGININE: GLYCINE AMIDINOTRANSFERASE (AGAT) KNOCKOUT MICE
Conference paper
Whittington HJ. et al, (2014), HEART, 100
Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity.
Journal article
Aksentijević D. et al, (2014), J Mol Cell Cardiol, 75, 76 - 87