Research groups
Colleges
Susann Bruche
Postdoctoral Research Associate
- Researcher Society Chair
Susann studied Biochemistry at Leipzig University, Germany, before joining Imperial College London for a MRes in Biomedical Research. She completed her PhD in the lab of Dr Vania Braga at Imperial College on epithelial biogenesis and adherens junction signalling, before joining the group of Dr Nicola Smart as a PostDoc investigate the role of alternative splicing in the regulation of heart repair after myocardial infarction. She is now working for Dr Sarah De Val and studies flow-responsive gene expression. Susann is a Junior Research Fellow at Wolfson College.
Key publications
Junction Mapper is a novel computer vision tool to decipher cell-cell contact phenotypes.
Journal article
Brezovjakova H. et al, (2019), Elife, 8
Thymosin β4 mediates vascular protection via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)
Working paper
MUNSHAW S. et al, (2019)
FRET-ting about RhoA signalling in heart and vasculature: a new tool in our cardiovascular toolbox
Journal article
(2018), Cardiovascular Research
The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts
Journal article
McCormack JJ. et al, (2017), Scientific Reports
Corrigendum: Defining functional interactions during biogenesis of epithelial junctions.
Journal article
Erasmus JC. et al, (2017), Nat Commun, 8
A genetically distinct lion (Panthera leo) population from Ethiopia
Journal article
Bruche S. et al, (2013), European Journal of Wildlife Research, 59, 215 - 225
Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.
Journal article
Dawson JC. et al, (2012), PLoS One, 7
Recent publications
The RNA-binding protein SRSF3 controls epicardial formation by regulating splicing and proliferation.
Journal article
Lupu I-E. et al, (2026), Development, 153
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development.
Preprint
Zhao J. et al, (2025)
Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development
Journal article
Zhao J. et al, (2025), eLife, 14