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Oxbridge BHF Centre of Regenerative Medicine


In early 2013 the Universities of Oxford, Cambridge & Bristol received a joint award of £2.5m from the British Heart Foundation to establish the Oxbridge BHF Centre of Regenerative Medicine (BHF CRM).

The Centre Director is Prof Paul Riley (Oxford), and the Centre administrator is Dr Tertia Softley (Oxford).

The Oxbridge BHF CRM brings together 26 world leading basic and translational research groups (13 based in Oxford, 12 based in Cambridge, and 1 based in Bristol) merging significant expertise in cardiovascular repair and regeneration (Oxford), wound healing (Bristol), with a major focus on stem cells (ESCs and iPSCs) and genetics in the context of regeneration (Cambridge).

"The BHF UK Cardiovascular Regenerative Medicine award will enable us to integrate expertise in developmental and stem cell biology, wound healing and inflammation across Oxford, Cambridge and Bristol to identify future therapeutic targets towards mending broken hearts. This will be underpinned by an emphasis on research training and a novel Oxbridge graduate student programme supported by the BHF award and will serve as an important stepping stone towards securing further funding in regenerative medicine" Prof Paul Riley.

Aims of the CRM

  • To make fundamental discoveries that provide new insights into cardiovascular stem cell function and potency
  • To harness the capacity of endogenous stem cell and progenitor cells for repair and regeneration
  • To exploit stem cells as tools for studying the molecular pathogenesis of human diseases and discovery of therapeutic agents
  • To nurture future generations of cardiovascular stem cell scientists in an intellectually invigorating environment of basic and translational research

CRM Studentships

The CRE has established a 4 year DPhil (PhD) studentship programme with students spending time in Oxford and time in Cambridge or Bristol, under joint supervision. Full details of the studentships are available.

BHF Centres of Regenerative Medicine

The Oxbridge BHF CRM is one of three BHF Centres of Regenerative Medicine, with the other Centres based in Imperial College London and the University of Edinburgh. The 3 Centres are funded by the BHF Mending Broken Hearts Appeal.